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Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice
H Wu, Z Song, M Hentzer,
Jens Bo Andersen
, S Molin,
M Givskov
,
Niels Høiby
348
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Keyphrases
Furanone
100%
Quorum Sensing
100%
Lung Infection
100%
Pseudomonas Aeruginosa (P. aeruginosa)
100%
Bacterial Quorum Sensing
41%
Therapeutic Effect
16%
N-acyl Homoserine Lactone
16%
Lung
16%
Bacterial Infection
16%
Pseudomonas Aeruginosa PAO1
16%
Infection Treatment
8%
Lung Pathology
8%
LasR
8%
Inhibiting Effect
8%
LuxR
8%
Biofilm Formation
8%
Green Fluorescent Protein
8%
Escherichia Coli
8%
Resistance to Antibiotics
8%
Antibiotics
8%
Marine Microalgae
8%
Mouse Model
8%
Chronic Lung Infection
8%
Delisea Pulchra
8%
Survival Time
8%
Quorum Systems
8%
Pharmacology, Toxicology and Pharmaceutical Science
Bacterial Clearance
100%
Bacterial Virulence
25%
Macroalga
12%