Synovial sarcoma mechanisms: a series of unfortunate events

Jesper Q Svejstrup

doi:10.1016/j.cell.2013.03.015

Synovial sarcoma mechanisms: a series of unfortunate events

Jesper Q Svejstrup

Morphogenesis and Differentiation Program

6 Citationer (Scopus)

Abstract

Human synovial sarcoma is caused by a chromosome translocation, which fuses DNA encoding SSX to that encoding the SS18 protein. Kadoch and Crabtree now show that the resulting cellular transformation stems from disruption of the normal architecture and function of the human SWI/SNF (BAF) complex.

Originalsprog	Engelsk
Tidsskrift	Cell
Vol/bind	153
Udgave nummer	1
Sider (fra-til)	11-2
Antal sider	2
ISSN	0092-8674
DOI	https://doi.org/10.1016/j.cell.2013.03.015
Status	Udgivet - 28 mar. 2013

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10.1016/j.cell.2013.03.015

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title = "Synovial sarcoma mechanisms: a series of unfortunate events",

abstract = "Human synovial sarcoma is caused by a chromosome translocation, which fuses DNA encoding SSX to that encoding the SS18 protein. Kadoch and Crabtree now show that the resulting cellular transformation stems from disruption of the normal architecture and function of the human SWI/SNF (BAF) complex.",

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AB - Human synovial sarcoma is caused by a chromosome translocation, which fuses DNA encoding SSX to that encoding the SS18 protein. Kadoch and Crabtree now show that the resulting cellular transformation stems from disruption of the normal architecture and function of the human SWI/SNF (BAF) complex.

U2 - 10.1016/j.cell.2013.03.015

DO - 10.1016/j.cell.2013.03.015

M3 - Journal article

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SN - 0092-8674

VL - 153

SP - 11

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JO - Cell

JF - Cell

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ER -

Synovial sarcoma mechanisms: a series of unfortunate events

Abstract

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