Susceptibility of muscovy (Cairina Moschata) and mallard ducks (Anas Platyrhynchos) to experimental infections by different genotypes of H5N1 avian influenza viruses

TY - JOUR

T1 - Susceptibility of muscovy (Cairina Moschata) and mallard ducks (Anas Platyrhynchos) to experimental infections by different genotypes of H5N1 avian influenza viruses

AU - Phuong, Do Quy

AU - Dung, Nguyen Tien

AU - Jørgensen, Poul Henrik

AU - Handberg, Kurt

AU - Vinh, Nguyen The

AU - Christensen, Jens Peter

PY - 2011/3/24

Y1 - 2011/3/24

N2 - It is a fact that in Viet Nam, Muscovy ducks are raised in large populations (approximately 8 million), usually kept in small flocks together with mallards and chickens. As a result, it is a great concern for epidemiologists to elucidate possible differences in relation to these species being exposed to infection with H5N1. To do this, an experimental study on infections with different genotypes of H5N1 in mallards and Muscovy ducks have been conducted, where it was found that the mortality of the inoculated Muscovy ducks was at least 80%, regardless of the virus strain employed. In contrast, the mortality of the mallards ranged from nil to 100%, which suggests that Muscovy ducks are more susceptible to HPAIV H5N1 infection in terms of disease development and mortality. It was also found that higher virus titers developed in vital organs of Muscovy ducks compared to mallards, particularly in the brain. Due to their high susceptibility, it is unlikely that Muscovy ducks act as a silent reservoir. The virus strains used in this study, to a certain degree, differed in their virulence properties to the bird species in question.

AB - It is a fact that in Viet Nam, Muscovy ducks are raised in large populations (approximately 8 million), usually kept in small flocks together with mallards and chickens. As a result, it is a great concern for epidemiologists to elucidate possible differences in relation to these species being exposed to infection with H5N1. To do this, an experimental study on infections with different genotypes of H5N1 in mallards and Muscovy ducks have been conducted, where it was found that the mortality of the inoculated Muscovy ducks was at least 80%, regardless of the virus strain employed. In contrast, the mortality of the mallards ranged from nil to 100%, which suggests that Muscovy ducks are more susceptible to HPAIV H5N1 infection in terms of disease development and mortality. It was also found that higher virus titers developed in vital organs of Muscovy ducks compared to mallards, particularly in the brain. Due to their high susceptibility, it is unlikely that Muscovy ducks act as a silent reservoir. The virus strains used in this study, to a certain degree, differed in their virulence properties to the bird species in question.

KW - Former LIFE faculty

KW - Eksperimental infection

KW - H5N1

KW - Avian influenza

KW - Ducks

KW - Muscovy ducks

KW - Mallard ducks

KW - H5N1

KW - Avian influenza

KW - Ducks

KW - Muscovy ducks

KW - Mallard ducks

KW - Experimental infection

U2 - 10.1016/j.vetmic.2010.09.007

DO - 10.1016/j.vetmic.2010.09.007

M3 - Journal article

C2 - 20943331

SN - 0378-1135

VL - 148

SP - 168

EP - 174

JO - Veterinary Microbiology

JF - Veterinary Microbiology

IS - 2-4

ER -