TY - JOUR
T1 - Survival and characteristics of pediatric salivary gland cancer
T2 - A systematic review and meta-analysis
AU - Zamani, Martin
AU - Grønhøj, Christian
AU - Schmidt Jensen, Jakob
AU - von Buchwald, Christian
AU - Charabi, Birgitte Wittenborg
AU - Hjuler, Thomas
N1 - © 2018 Wiley Periodicals, Inc.
PY - 2019/3
Y1 - 2019/3
N2 - A systematic search of PubMed, EMBASE, and the Cochrane Library for studies from 2000 to 2017 including children aged 0-19 with salivary gland cancer was performed. In 19 studies, 749 children (median age of 14.2 years, female to male ratio of 1.4:1) were included; 72% had parotid tumors and 95% underwent surgery, of whom 65% had surgery alone and 24% with adjuvant radiotherapy. Low-grade and stage mucoepidermoid carcinoma were the most frequent cancer. The 5-year overall- and disease-free survival was 94% and 83%. Recurrence was observed in 20% at a median of 1.1 years from diagnosis.
AB - A systematic search of PubMed, EMBASE, and the Cochrane Library for studies from 2000 to 2017 including children aged 0-19 with salivary gland cancer was performed. In 19 studies, 749 children (median age of 14.2 years, female to male ratio of 1.4:1) were included; 72% had parotid tumors and 95% underwent surgery, of whom 65% had surgery alone and 24% with adjuvant radiotherapy. Low-grade and stage mucoepidermoid carcinoma were the most frequent cancer. The 5-year overall- and disease-free survival was 94% and 83%. Recurrence was observed in 20% at a median of 1.1 years from diagnosis.
U2 - 10.1002/pbc.27543
DO - 10.1002/pbc.27543
M3 - Review
C2 - 30378272
SN - 1545-5009
VL - 66
JO - Pediatric Blood & Cancer
JF - Pediatric Blood & Cancer
IS - 3
M1 - e27543
ER -
