Successful pregnancy in a woman previously suffering from β-thalassemia following transplantation of ovarian tissue cryopreserved before puberty

TY - JOUR

T1 - Successful pregnancy in a woman previously suffering from β-thalassemia following transplantation of ovarian tissue cryopreserved before puberty

AU - Matthews, Sara J.

AU - Picton, Helen

AU - Ernst, Erik

AU - Andersen, Claus Y.

PY - 2018/8/1

Y1 - 2018/8/1

N2 - Ovarian tissue removed from a 9-year-old girl suffering from thalassemia was kept deep-frozen for 14 years before being transplanted back to the now adult woman. Subsequently, she conceived following IVF treatment and delivered a healthy baby where the oocyte derived from the transplanted tissue. This is the frst woman worldwide to have a baby where the ovarian tissue was frozen pre-pubertally and expand the therapeutic options for rare genetic diseases like thalassemia and girls who suffer from childhood cancer.

AB - Ovarian tissue removed from a 9-year-old girl suffering from thalassemia was kept deep-frozen for 14 years before being transplanted back to the now adult woman. Subsequently, she conceived following IVF treatment and delivered a healthy baby where the oocyte derived from the transplanted tissue. This is the frst woman worldwide to have a baby where the ovarian tissue was frozen pre-pubertally and expand the therapeutic options for rare genetic diseases like thalassemia and girls who suffer from childhood cancer.

KW - Fertility preservation

KW - Freezing

KW - Ovary

KW - Thalassemia

KW - Transplantation

UR - http://www.scopus.com/inward/record.url?scp=85049748659&partnerID=8YFLogxK

U2 - 10.23736/S0026-4784.18.04240-5

DO - 10.23736/S0026-4784.18.04240-5

M3 - Review

C2 - 29696941

AN - SCOPUS:85049748659

SN - 0026-4784

VL - 70

SP - 432

EP - 435

JO - Minerva Ginecologica

JF - Minerva Ginecologica

IS - 4

ER -