Stunting, wasting and breastfeeding as correlates of body composition in Cambodian children at 6 and 15 months of age

Jutta Kloppenborg Heick Skau; Benedikte Grenov; Chhoun Chamnan; Chea Mary; Frank T Wieringa; Marjoleine A Dijkhuizen; Christian Ritz; Jonathan C Wells; Jacques Berger; Suzanne Filteau; Nanna Roos; Kim F. Michaelsen; Henrik Friis

doi:10.1017/s0007114518003884

Stunting, wasting and breastfeeding as correlates of body composition in Cambodian children at 6 and 15 months of age

Jutta Kloppenborg Heick Skau, Benedikte Grenov, Chhoun Chamnan, Chea Mary, Frank T Wieringa, Marjoleine A Dijkhuizen, Christian Ritz, Jonathan C Wells, Jacques Berger, Suzanne Filteau, Nanna Roos, Kim F. Michaelsen, Henrik Friis

Ernæring og Sundhed hos børn og voksne

4 Citationer (Scopus)

Abstract

The study aimed at assessing stunting, wasting and breast-feeding as correlates of body composition in Cambodian children. As part of a nutrition trial (ISRCTN19918531), fat mass (FM) and fat-free mass (FFM) were measured using ²H dilution at 6 and 15 months of age. Of 419 infants enrolled, 98 % were breastfed, 15 % stunted and 4 % wasted at 6 months. At 15 months, 78 % were breastfed, 24 % stunted and 11 % wasted. Those not breastfed had lower FMI at 6 months but not at 15 months. Stunted children had lower FM at 6 months and lower FFM at 6 and 15 months compared with children with length-for-age z ≥0. Stunting was not associated with height-adjusted indexes fat mass index (FMI) or fat-free mass index (FFMI). Wasted children had lower FM, FFM, FMI and FFMI at 6 and 15 months compared with children with weight-for-length z (WLZ) ≥0. Generally, FFM and FFMI deficits increased with age, whereas FM and FMI deficits decreased, reflecting interactions between age and WLZ. For example, the FFM deficits were-0·99 (95 % CI-1·26,-0·72) kg at 6 months and-1·44 (95 % CI-1·69;-1·19) kg at 15 months (interaction, P<0·05), while the FMI deficits were-2·12 (95 % CI-2·53,-1·72) kg/m² at 6 months and-1·32 (95 % CI-1·77,-0·87) kg/m² at 15 months (interaction, P<0·05). This indicates that undernourished children preserve body fat at the detriment of fat-free tissue, which may have long-term consequences for health and working capacity.

Originalsprog	Engelsk
Tidsskrift	British Journal of Nutrition
Vol/bind	121
Sider (fra-til)	688-698
Antal sider	11
ISSN	0007-1145
DOI	https://doi.org/10.1017/s0007114518003884
Status	Udgivet - 28 mar. 2019

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10.1017/s0007114518003884

div-class-title-stunting-wasting-and-breast-feeding-as-correlates-of-body-composition-in-cambodian-children-at-6-and-15-months-of-age-div.pdfForlagets udgivne version, 481 KB

Citationsformater

Skau, J. K. H., Grenov, B., Chamnan, C., Mary, C., Wieringa, F. T., Dijkhuizen, M. A., Ritz, C., Wells, J. C., Berger, J., Filteau, S., Roos, N., Michaelsen, K. F., & Friis, H. (2019). Stunting, wasting and breastfeeding as correlates of body composition in Cambodian children at 6 and 15 months of age. British Journal of Nutrition, 121, 688-698. https://doi.org/10.1017/s0007114518003884

Skau, JKH, Grenov, B, Chamnan, C, Mary, C, Wieringa, FT, Dijkhuizen, MA, Ritz, C, Wells, JC, Berger, J, Filteau, S, Roos, N , Michaelsen, KF & Friis, H 2019, 'Stunting, wasting and breastfeeding as correlates of body composition in Cambodian children at 6 and 15 months of age', British Journal of Nutrition, bind 121, s. 688-698. https://doi.org/10.1017/s0007114518003884

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title = "Stunting, wasting and breastfeeding as correlates of body composition in Cambodian children at 6 and 15 months of age",

abstract = "The study aimed at assessing stunting, wasting and breast-feeding as correlates of body composition in Cambodian children. As part of a nutrition trial (ISRCTN19918531), fat mass (FM) and fat-free mass (FFM) were measured using 2H dilution at 6 and 15 months of age. Of 419 infants enrolled, 98 % were breastfed, 15 % stunted and 4 % wasted at 6 months. At 15 months, 78 % were breastfed, 24 % stunted and 11 % wasted. Those not breastfed had lower FMI at 6 months but not at 15 months. Stunted children had lower FM at 6 months and lower FFM at 6 and 15 months compared with children with length-for-age z ≥0. Stunting was not associated with height-adjusted indexes fat mass index (FMI) or fat-free mass index (FFMI). Wasted children had lower FM, FFM, FMI and FFMI at 6 and 15 months compared with children with weight-for-length z (WLZ) ≥0. Generally, FFM and FFMI deficits increased with age, whereas FM and FMI deficits decreased, reflecting interactions between age and WLZ. For example, the FFM deficits were-0·99 (95 % CI-1·26,-0·72) kg at 6 months and-1·44 (95 % CI-1·69;-1·19) kg at 15 months (interaction, P<0·05), while the FMI deficits were-2·12 (95 % CI-2·53,-1·72) kg/m2 at 6 months and-1·32 (95 % CI-1·77,-0·87) kg/m2 at 15 months (interaction, P<0·05). This indicates that undernourished children preserve body fat at the detriment of fat-free tissue, which may have long-term consequences for health and working capacity.",

keywords = "Faculty of Science, Body composition, Fat-free mass, Fat mass, Infancy, Childhood, Breastfeeding, Stunting, Wasting",

author = "Skau, {Jutta Kloppenborg Heick} and Benedikte Grenov and Chhoun Chamnan and Chea Mary and Wieringa, {Frank T} and Dijkhuizen, {Marjoleine A} and Christian Ritz and Wells, {Jonathan C} and Jacques Berger and Suzanne Filteau and Nanna Roos and Michaelsen, {Kim F.} and Henrik Friis",

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T1 - Stunting, wasting and breastfeeding as correlates of body composition in Cambodian children at 6 and 15 months of age

AU - Skau, Jutta Kloppenborg Heick

AU - Grenov, Benedikte

AU - Chamnan, Chhoun

AU - Mary, Chea

AU - Wieringa, Frank T

AU - Dijkhuizen, Marjoleine A

AU - Ritz, Christian

AU - Wells, Jonathan C

AU - Berger, Jacques

AU - Filteau, Suzanne

AU - Roos, Nanna

AU - Michaelsen, Kim F.

AU - Friis, Henrik

N1 - CURIS 2019 NEXS 063

PY - 2019/3/28

Y1 - 2019/3/28

N2 - The study aimed at assessing stunting, wasting and breast-feeding as correlates of body composition in Cambodian children. As part of a nutrition trial (ISRCTN19918531), fat mass (FM) and fat-free mass (FFM) were measured using 2H dilution at 6 and 15 months of age. Of 419 infants enrolled, 98 % were breastfed, 15 % stunted and 4 % wasted at 6 months. At 15 months, 78 % were breastfed, 24 % stunted and 11 % wasted. Those not breastfed had lower FMI at 6 months but not at 15 months. Stunted children had lower FM at 6 months and lower FFM at 6 and 15 months compared with children with length-for-age z ≥0. Stunting was not associated with height-adjusted indexes fat mass index (FMI) or fat-free mass index (FFMI). Wasted children had lower FM, FFM, FMI and FFMI at 6 and 15 months compared with children with weight-for-length z (WLZ) ≥0. Generally, FFM and FFMI deficits increased with age, whereas FM and FMI deficits decreased, reflecting interactions between age and WLZ. For example, the FFM deficits were-0·99 (95 % CI-1·26,-0·72) kg at 6 months and-1·44 (95 % CI-1·69;-1·19) kg at 15 months (interaction, P<0·05), while the FMI deficits were-2·12 (95 % CI-2·53,-1·72) kg/m2 at 6 months and-1·32 (95 % CI-1·77,-0·87) kg/m2 at 15 months (interaction, P<0·05). This indicates that undernourished children preserve body fat at the detriment of fat-free tissue, which may have long-term consequences for health and working capacity.

AB - The study aimed at assessing stunting, wasting and breast-feeding as correlates of body composition in Cambodian children. As part of a nutrition trial (ISRCTN19918531), fat mass (FM) and fat-free mass (FFM) were measured using 2H dilution at 6 and 15 months of age. Of 419 infants enrolled, 98 % were breastfed, 15 % stunted and 4 % wasted at 6 months. At 15 months, 78 % were breastfed, 24 % stunted and 11 % wasted. Those not breastfed had lower FMI at 6 months but not at 15 months. Stunted children had lower FM at 6 months and lower FFM at 6 and 15 months compared with children with length-for-age z ≥0. Stunting was not associated with height-adjusted indexes fat mass index (FMI) or fat-free mass index (FFMI). Wasted children had lower FM, FFM, FMI and FFMI at 6 and 15 months compared with children with weight-for-length z (WLZ) ≥0. Generally, FFM and FFMI deficits increased with age, whereas FM and FMI deficits decreased, reflecting interactions between age and WLZ. For example, the FFM deficits were-0·99 (95 % CI-1·26,-0·72) kg at 6 months and-1·44 (95 % CI-1·69;-1·19) kg at 15 months (interaction, P<0·05), while the FMI deficits were-2·12 (95 % CI-2·53,-1·72) kg/m2 at 6 months and-1·32 (95 % CI-1·77,-0·87) kg/m2 at 15 months (interaction, P<0·05). This indicates that undernourished children preserve body fat at the detriment of fat-free tissue, which may have long-term consequences for health and working capacity.

KW - Faculty of Science

KW - Body composition

KW - Fat-free mass

KW - Fat mass

KW - Infancy

KW - Childhood

KW - Breastfeeding

KW - Stunting

KW - Wasting

U2 - 10.1017/s0007114518003884

DO - 10.1017/s0007114518003884

M3 - Journal article

C2 - 30670108

SN - 0007-1145

VL - 121

SP - 688

EP - 698

JO - British Journal of Nutrition

JF - British Journal of Nutrition

ER -

Stunting, wasting and breastfeeding as correlates of body composition in Cambodian children at 6 and 15 months of age

Abstract

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