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Studying furosemide solubilization using an
in vitro
model simulating gastrointestinal digestion and drug solubilization in neonates and young infants
Mette Klitgaard
, Philip Jonas Sassene, Arzu Selen,
Anette Müllertz
,
Ragna Berthelsen
8
Citationer (Scopus)
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Keyphrases
Young Infants
100%
Neonatal Infants
100%
Furosemide
100%
Drug Solubility
100%
In Vitro Model
100%
Model Simulating
100%
Gastrointestinal Digestion
100%
Digestion
80%
Infant Population
40%
Dosage Forms
40%
Digestive Enzymes
40%
Oral Performance
40%
Model Setting
40%
Gastrointestinal Tract
20%
Solubilization Capacity
20%
Human Neonates
20%
Aqueous Phase
20%
Medium Volume
20%
In Vitro Lipolysis Model
20%
Physiologically Relevant
20%
Drug Powders
20%
Stomach
20%
Population Aging
20%
Digestive Properties
20%
Small Intestine
20%
In Vitro Data
20%
Food Effect
20%
Immediate Release Tablets
20%
Pharmacology, Toxicology and Pharmaceutical Science
Drug Solubilisation
100%
Furosemide
100%
Dosage Form
40%
Tablet
20%