TY - JOUR
T1 - Structure and function of mammalian cilia
AU - Satir, Peter
AU - Christensen, Søren T
N1 - Keywords: Animals; Cell Movement; Cilia; Ciliary Motility Disorders; Humans
PY - 2008
Y1 - 2008
N2 - In the past half century, beginning with electron microscopic studies of 9 + 2 motile and 9 + 0 primary cilia, novel insights have been obtained regarding the structure and function of mammalian cilia. All cilia can now be viewed as sensory cellular antennae that coordinate a large number of cellular signaling pathways, sometimes coupling the signaling to ciliary motility or alternatively to cell division and differentiation. This view has had unanticipated consequences for our understanding of developmental processes and human disease.
AB - In the past half century, beginning with electron microscopic studies of 9 + 2 motile and 9 + 0 primary cilia, novel insights have been obtained regarding the structure and function of mammalian cilia. All cilia can now be viewed as sensory cellular antennae that coordinate a large number of cellular signaling pathways, sometimes coupling the signaling to ciliary motility or alternatively to cell division and differentiation. This view has had unanticipated consequences for our understanding of developmental processes and human disease.
U2 - 10.1007/s00418-008-0416-9
DO - 10.1007/s00418-008-0416-9
M3 - Journal article
C2 - 18365235
SN - 0948-6143
VL - 129
SP - 687
EP - 693
JO - Histochemistry and Cell Biology
JF - Histochemistry and Cell Biology
IS - 6
ER -
