Stimulation of pancreatic beta-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways.

Medicin og biovidenskab

• 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 15%
• Adenylyl Cyclases 6%
• Cell Line 3%
• Colforsin 13%
• Cyclic AMP-Dependent Protein Kinases 6%
• Cyclin D1 83%
• Cyclin D2 18%
• Cyclin D3 9%
• Cyclins 7%
• Cytokines 3%
• G1 Phase 6%
• Gastric Inhibitory Polypeptide 75%
• Glucagon 6%
• Glucagon-Like Peptide 1 90%
• Growth 3%
• H-89 dihydrochloride hydrate 10%
• Hormones 4%
• Human Growth Hormone 23%
• Incretins 100%
• Insulin-Secreting Cells 82%
• Insulinoma 8%
• Intercellular Signaling Peptides and Proteins 5%
• Islets of Langerhans 12%
• Liraglutide 18%
• Luciferases 5%
• Maintenance 4%
• MAP Kinase Kinase 3 10%
• Messenger RNA 7%
• Mitogen-Activated Protein Kinase 1 7%
• Mitogen-Activated Protein Kinase Kinases 13%
• Mitosis 6%
• N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide 8%
• p38 Mitogen-Activated Protein Kinases 6%
• Phase Transition 8%
• Phosphotransferases 4%
• Protein Kinase Inhibitors 6%
• Proteins 2%
• S Phase 6%
• SB 203580 7%
• Transfection 5%
• Wortmannin 15%