TY - JOUR
T1 - Somatic growth in 94 single ventricle children -- comparing systemic right and left ventricle patients
AU - Hessel, Trine witzner
AU - Greisen, Gorm
AU - Idorn, Lars
AU - Reimers, Jesper Irving
N1 - ©2012 The Author(s)/Acta Paediatrica ©2012 Foundation Acta Paediatrica.
PY - 2013/1
Y1 - 2013/1
N2 - Aim: We sought to compare and assess growth in single ventricle children with a systemic right or left ventricle in five time periods: at birth, before neonatal surgery, before the Glenn anastomosis and finally before and after the Fontan operation to 11years of age. Methods: We reviewed medical records on 116 single ventricle patients operated at Rigshospitalet, Denmark from 1987 to 2007. Surgical procedures, feeding route, hemodynamic variables and anthropometric measurements such as weight and height were registered and converted to z-scores. Results: Ninety four single ventricle patients were included for analysis. Gestational age and birth weight was not significantly different between the left and right ventricle group. Before neonatal surgery and before the Glenn anastomosis, both groups showed equal growth retardation. However, a significant difference in catch-up growth was found before the Fontan operation. Thus, patients in the right ventricle group had a smaller median weight-for-age z-score compared with the left ventricle group in the pre-Fontan period (-1.9 and -1.6; p=0.049) and in the post-Fontan period (-1.1 and -0.7; p=0.034). Conclusion: After the Glenn anastomosis single ventricle children with a systemic left ventricle have better weight gain compared with children with a systemic right ventricle.
AB - Aim: We sought to compare and assess growth in single ventricle children with a systemic right or left ventricle in five time periods: at birth, before neonatal surgery, before the Glenn anastomosis and finally before and after the Fontan operation to 11years of age. Methods: We reviewed medical records on 116 single ventricle patients operated at Rigshospitalet, Denmark from 1987 to 2007. Surgical procedures, feeding route, hemodynamic variables and anthropometric measurements such as weight and height were registered and converted to z-scores. Results: Ninety four single ventricle patients were included for analysis. Gestational age and birth weight was not significantly different between the left and right ventricle group. Before neonatal surgery and before the Glenn anastomosis, both groups showed equal growth retardation. However, a significant difference in catch-up growth was found before the Fontan operation. Thus, patients in the right ventricle group had a smaller median weight-for-age z-score compared with the left ventricle group in the pre-Fontan period (-1.9 and -1.6; p=0.049) and in the post-Fontan period (-1.1 and -0.7; p=0.034). Conclusion: After the Glenn anastomosis single ventricle children with a systemic left ventricle have better weight gain compared with children with a systemic right ventricle.
U2 - 10.1111/apa.12032
DO - 10.1111/apa.12032
M3 - Journal article
C2 - 22994405
SN - 0803-5253
VL - 102
SP - 35
EP - 39
JO - Acta Paediatrica, International Journal of Paediatrics, Supplement
JF - Acta Paediatrica, International Journal of Paediatrics, Supplement
IS - 1
ER -