SNPTools: A software tool for visualization and analysis of microarray data

Frank J. Sørensen; Claus L. Andersen; Carsten Wiuf

doi:10.1093/bioinformatics/btm122

SNPTools: A software tool for visualization and analysis of microarray data

Frank J. Sørensen, Claus L. Andersen, Carsten Wiuf^*

^*Corresponding author af dette arbejde

3 Citationer (Scopus)

Abstract

Summary: We have created a software tool, SNPTools, for analysis and visualization of microarray data, mainly SNP array data. The software can analyse and find differences in intensity levels between groups of arrays and identify segments of SNPs (genes, clones), where the intensity levels differ significantly between the groups. In addition, SNPTools can show jointly loss-of-heterozygosity (LOH) data (derived from genotypes) and intensity data for paired samples of tumour and normal arrays. The output graphs can be manipulated in various ways to modify and adjust the layout. A wizard allows options and parameters to be changed easily and graphs replotted. All output can be saved in various formats, and also re-opened in SNPTools for further analysis. For explorative use, SNPTools allows various genome information to be loaded onto the graphs.

Originalsprog	Engelsk
Tidsskrift	Bioinformatics
Vol/bind	23
Udgave nummer	12
Sider (fra-til)	1550-1552
Antal sider	3
ISSN	1367-4803
DOI	https://doi.org/10.1093/bioinformatics/btm122
Status	Udgivet - 15 jun. 2007
Udgivet eksternt	Ja

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title = "SNPTools: A software tool for visualization and analysis of microarray data",

abstract = "Summary: We have created a software tool, SNPTools, for analysis and visualization of microarray data, mainly SNP array data. The software can analyse and find differences in intensity levels between groups of arrays and identify segments of SNPs (genes, clones), where the intensity levels differ significantly between the groups. In addition, SNPTools can show jointly loss-of-heterozygosity (LOH) data (derived from genotypes) and intensity data for paired samples of tumour and normal arrays. The output graphs can be manipulated in various ways to modify and adjust the layout. A wizard allows options and parameters to be changed easily and graphs replotted. All output can be saved in various formats, and also re-opened in SNPTools for further analysis. For explorative use, SNPTools allows various genome information to be loaded onto the graphs.",

author = "S{\o}rensen, {Frank J.} and Andersen, {Claus L.} and Carsten Wiuf",

year = "2007",

month = jun,

day = "15",

doi = "10.1093/bioinformatics/btm122",

language = "English",

volume = "23",

pages = "1550--1552",

journal = "Bioinformatics (Online)",

issn = "1367-4811",

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TY - JOUR

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T2 - A software tool for visualization and analysis of microarray data

AU - Sørensen, Frank J.

AU - Andersen, Claus L.

AU - Wiuf, Carsten

PY - 2007/6/15

Y1 - 2007/6/15

N2 - Summary: We have created a software tool, SNPTools, for analysis and visualization of microarray data, mainly SNP array data. The software can analyse and find differences in intensity levels between groups of arrays and identify segments of SNPs (genes, clones), where the intensity levels differ significantly between the groups. In addition, SNPTools can show jointly loss-of-heterozygosity (LOH) data (derived from genotypes) and intensity data for paired samples of tumour and normal arrays. The output graphs can be manipulated in various ways to modify and adjust the layout. A wizard allows options and parameters to be changed easily and graphs replotted. All output can be saved in various formats, and also re-opened in SNPTools for further analysis. For explorative use, SNPTools allows various genome information to be loaded onto the graphs.

AB - Summary: We have created a software tool, SNPTools, for analysis and visualization of microarray data, mainly SNP array data. The software can analyse and find differences in intensity levels between groups of arrays and identify segments of SNPs (genes, clones), where the intensity levels differ significantly between the groups. In addition, SNPTools can show jointly loss-of-heterozygosity (LOH) data (derived from genotypes) and intensity data for paired samples of tumour and normal arrays. The output graphs can be manipulated in various ways to modify and adjust the layout. A wizard allows options and parameters to be changed easily and graphs replotted. All output can be saved in various formats, and also re-opened in SNPTools for further analysis. For explorative use, SNPTools allows various genome information to be loaded onto the graphs.

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DO - 10.1093/bioinformatics/btm122

M3 - Journal article

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AN - SCOPUS:34547840182

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JO - Bioinformatics (Online)

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ER -

SNPTools: A software tool for visualization and analysis of microarray data

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