Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive side chain peroxides on tyrosine residues

Fysik og astronomi

• tyrosine 59%
• peroxides 53%
• proteins 33%
• peptides 30%
• oxidation 30%
• alcohols 29%
• rings 28%
• oxygen 25%
• decay 23%
• propionic acid 23%
• indoles 21%
• carboxylic acids 20%
• liquid chromatography 18%
• cataracts 18%
• spectroscopic analysis 17%
• pathology 16%
• light ions 16%
• metal ions 15%
• enzymes 14%
• half life 14%
• cleavage 14%
• closures 13%
• cancer 13%
• electron paramagnetic resonance 12%
• nuclear magnetic resonance 11%
• trapping 10%
• damage 9%
• performance 6%

Medicin og biovidenskab

• tyrosine peroxide 100%
• Singlet Oxygen 59%
• Peroxides 53%
• Hydrogen Peroxide 42%
• Ultraviolet Rays 28%
• indole-2-carboxylic acid 28%
• phloretic acid 27%
• Light Metals 26%
• Spin Trapping 21%
• Alcohols 21%
• Azides 19%
• Sunburn 19%
• Electron Spin Resonance Spectroscopy 18%
• Peptides 17%
• Proteins 15%
• Skin Neoplasms 14%
• Cataract 13%
• Magnetic Resonance Spectroscopy 11%
• Ions 11%
• High Pressure Liquid Chromatography 11%
• Temperature 10%
• Light 9%
• Pathology 8%
• Enzymes 7%

Kemiske forbindelser

• Tyrosine Residue 48%
• Hydroperoxide 43%
• Peroxide 37%
• Tyr-Tyr 25%
• Met-Trp 25%
• Trp-Tyr 23%
• Photochemical Method 20%
• Oxidation Reaction 18%
• Protein 17%
• Alcohol 16%
• Spin Trapping 16%
• Peptide 16%
• Propionic Acid 15%
• Spectroscopic Analysis 13%
• Reaction Half Life 13%
• Chemical Method 13%
• Azide 12%
• Ring Opening Reaction 12%
• EPR Spectroscopy 12%
• High-Pressure Liquid Chromatography 10%
• Cleavage 9%
• NMR Spectroscopy 9%
• Rate Constant 9%
• Metal Ion 8%
• Dioxygen 6%
• Mixture 6%
• Reaction Yield 5%
• Acid 4%