Short-term exposure to fine and coarse particles and mortality: A multicity time-series study in East Asia

TY - JOUR

T1 - Short-term exposure to fine and coarse particles and mortality

T2 - A multicity time-series study in East Asia

AU - Lee, Hyewon

AU - Honda, Yasushi

AU - Hashizume, Masahiro

AU - Guo, Yue Leon

AU - Wu, Chang-Fu

AU - Kan, Haidong

AU - Jung, Kweon

AU - Lim, Youn-Hee

AU - Yi, Seungmuk

AU - Kim, Ho

N1 - Copyright © 2015 Elsevier Ltd. All rights reserved.

PY - 2015/12/1

Y1 - 2015/12/1

N2 - Few studies on size-specific health effects of particulate matter have been conducted in Asia. We examined the association between both fine and coarse particles (PM2.5 and PM10-2.5) and mortality across 11 East Asian cities from 4 countries (Korea, Japan, Taiwan, and China). We performed a two-stage analysis: we generated city-specific estimates using a time-series analysis with a generalized additive model (Quasi-Poisson distribution), and estimated the overall effects by conducting a meta-analysis. Each 10-μg/m(3) increase in PM2.5 (lag01) was associated with an increase of 0.38% (95% confidence interval = 0.21%-0.55%) in all causes mortality, 0.96% (0.46%-1.46%) in cardiovascular mortality, and 1% (0.23%-1.78%) in respiratory mortality. Each 10-μg/m(3) increase in PM10-2.5 (lag01) was associated with cardiovascular mortality (0.69%, [0.05%-1.33%]), although this association attenuated after controlling for other pollutants, especially PM2.5. Increased mortality was associated with increasing PM2.5 and PM10-2.5 concentrations over 11 East Asian cities.

AB - Few studies on size-specific health effects of particulate matter have been conducted in Asia. We examined the association between both fine and coarse particles (PM2.5 and PM10-2.5) and mortality across 11 East Asian cities from 4 countries (Korea, Japan, Taiwan, and China). We performed a two-stage analysis: we generated city-specific estimates using a time-series analysis with a generalized additive model (Quasi-Poisson distribution), and estimated the overall effects by conducting a meta-analysis. Each 10-μg/m(3) increase in PM2.5 (lag01) was associated with an increase of 0.38% (95% confidence interval = 0.21%-0.55%) in all causes mortality, 0.96% (0.46%-1.46%) in cardiovascular mortality, and 1% (0.23%-1.78%) in respiratory mortality. Each 10-μg/m(3) increase in PM10-2.5 (lag01) was associated with cardiovascular mortality (0.69%, [0.05%-1.33%]), although this association attenuated after controlling for other pollutants, especially PM2.5. Increased mortality was associated with increasing PM2.5 and PM10-2.5 concentrations over 11 East Asian cities.

KW - Aged

KW - Air Pollutants/adverse effects

KW - Cities/epidemiology

KW - Environmental Exposure/adverse effects

KW - Far East/epidemiology

KW - Humans

KW - Models, Theoretical

KW - Mortality

KW - Particle Size

KW - Particulate Matter/adverse effects

KW - Poisson Distribution

U2 - 10.1016/j.envpol.2015.08.036

DO - 10.1016/j.envpol.2015.08.036

M3 - Journal article

C2 - 26340298

SN - 0269-7491

VL - 207

SP - 43

EP - 51

JO - Environmental Pollution

JF - Environmental Pollution

ER -