Seasonal changes in vitamin D status among Danish adolescent girls and elderly women: the influence of sun exposure and vitamin D intake

TY - JOUR

T1 - Seasonal changes in vitamin D status among Danish adolescent girls and elderly women

T2 - the influence of sun exposure and vitamin D intake

AU - Andersen, R

AU - Brot, C

AU - Jakobsen, J

AU - Mejborn, Heddie

AU - Mølgaard, Christian

AU - Skovgaard, Lene Theil

AU - Trolle, E

AU - Tetens, I

AU - Ovesen, L

N1 - CURIS 2013 NEXS 144

PY - 2013/3

Y1 - 2013/3

N2 - Background/objectives:To determine seasonal variation in vitamin D status in healthy Caucasian adolescent girls and elderly community-dwelling women living in Denmark, and to quantify the impact of sun exposure and intake on the seasonal changes in vitamin D status.Subjects/methods:A 1-year longitudinal observational study of 54 girls (11-13 years) and 52 women (70-75 years). The participants were examined three times (winter-summer-winter). Serum 25-hydroxyvitamin D (S-25OHD) concentration and vitamin D intake were measured at each visit. Sun exposure was measured during summer.Results:S-25OHD concentrations (winter, summer, winter) were median (25, 75 percentiles) 23.4 (16.5, 36.4), 60.3 (42.7, 67.7), 29.5 (22.2, 40.4) and 47.2 (27.3, 61.1), 67.3 (35.1, 79.2), 50.5 (32.7, 65.5)nmol/l for girls and women, respectively. The usual sun habits were determinant (P=0.002) for change in vitamin D status from winter to summer. Vitamin D intake from supplements (P<0.0001) and diet (P=0.002) were determinants for change in vitamin D status from summer to winter. Winter vitamin D status of 50 nmol/l is achievable when vitamin D status the previous summer was ∼100 nmol/l. If summer vitamin D status is only ∼60 nmol/l, vitamin D status the following winter would be ∼28 nmol/l.Conclusions:Low vitamin D status among adolescent girls and elderly women during two consecutive winter seasons, improved vitamin D status during the summer and better vitamin D status in women than in girls was found. The estimations show that a summer S-25OHD concentration ∼100 nmol/l is needed to achieve a concentration of ∼50 nmol/l the following winter.

AB - Background/objectives:To determine seasonal variation in vitamin D status in healthy Caucasian adolescent girls and elderly community-dwelling women living in Denmark, and to quantify the impact of sun exposure and intake on the seasonal changes in vitamin D status.Subjects/methods:A 1-year longitudinal observational study of 54 girls (11-13 years) and 52 women (70-75 years). The participants were examined three times (winter-summer-winter). Serum 25-hydroxyvitamin D (S-25OHD) concentration and vitamin D intake were measured at each visit. Sun exposure was measured during summer.Results:S-25OHD concentrations (winter, summer, winter) were median (25, 75 percentiles) 23.4 (16.5, 36.4), 60.3 (42.7, 67.7), 29.5 (22.2, 40.4) and 47.2 (27.3, 61.1), 67.3 (35.1, 79.2), 50.5 (32.7, 65.5)nmol/l for girls and women, respectively. The usual sun habits were determinant (P=0.002) for change in vitamin D status from winter to summer. Vitamin D intake from supplements (P<0.0001) and diet (P=0.002) were determinants for change in vitamin D status from summer to winter. Winter vitamin D status of 50 nmol/l is achievable when vitamin D status the previous summer was ∼100 nmol/l. If summer vitamin D status is only ∼60 nmol/l, vitamin D status the following winter would be ∼28 nmol/l.Conclusions:Low vitamin D status among adolescent girls and elderly women during two consecutive winter seasons, improved vitamin D status during the summer and better vitamin D status in women than in girls was found. The estimations show that a summer S-25OHD concentration ∼100 nmol/l is needed to achieve a concentration of ∼50 nmol/l the following winter.

U2 - 10.1038/ejcn.2013.3

DO - 10.1038/ejcn.2013.3

M3 - Journal article

C2 - 23388663

SN - 0954-3007

VL - 67

SP - 270

EP - 274

JO - European Journal of Clinical Nutrition

JF - European Journal of Clinical Nutrition

IS - 3

ER -