Roll-to-plate fabrication of microfluidic devices with rheology-modified thiol-ene resins

TY - JOUR

T1 - Roll-to-plate fabrication of microfluidic devices with rheology-modified thiol-ene resins

AU - Senkbeil, Silja

AU - Aho, Johanna

AU - Yde, Leif

AU - Lindvold, Lars R.

AU - Stensborg, Jan F.

AU - Rantanen, Jukka

AU - Lafleur, Josiane P.

AU - Kutter, Jörg P.

PY - 2016/6/20

Y1 - 2016/6/20

N2 - In this paper, the replication possibilities of microfluidic channels by UV-roll-to-plate fabrication were investigated and a study of rheology-modified thiol-ene for the application in such a UV-roll-to-plate setup was conducted. The system allows the manufacture of channels with aspect ratios of 2:1 and a maximal channel depth of 90 μm as well as the sealing of the finished devices with patterning and sealing speeds of up to 19 m min-1. By adding fumed silica nanoparticles to the uncured resins, it was possible to alter the rheological behavior of the resin system to fabricate shallow microfluidic channels with 40 × 95 μm cross-sectional dimensions. Moreover, deeper (90 μm) channels can be fabricated with highly viscous resins based on thiol-terminated oligomers. As a demonstration, capillary electrophoresis chips were prepared and tested for a simple separation of two fluorescent dyes.

AB - In this paper, the replication possibilities of microfluidic channels by UV-roll-to-plate fabrication were investigated and a study of rheology-modified thiol-ene for the application in such a UV-roll-to-plate setup was conducted. The system allows the manufacture of channels with aspect ratios of 2:1 and a maximal channel depth of 90 μm as well as the sealing of the finished devices with patterning and sealing speeds of up to 19 m min-1. By adding fumed silica nanoparticles to the uncured resins, it was possible to alter the rheological behavior of the resin system to fabricate shallow microfluidic channels with 40 × 95 μm cross-sectional dimensions. Moreover, deeper (90 μm) channels can be fabricated with highly viscous resins based on thiol-terminated oligomers. As a demonstration, capillary electrophoresis chips were prepared and tested for a simple separation of two fluorescent dyes.

KW - microfluidic device

KW - rheology modification

KW - roll-to-roll fabrication

KW - thiol-ene polymers

UR - http://www.scopus.com/inward/record.url?scp=84979642303&partnerID=8YFLogxK

U2 - 10.1088/0960-1317/26/7/075014

DO - 10.1088/0960-1317/26/7/075014

M3 - Journal article

AN - SCOPUS:84979642303

SN - 0960-1317

VL - 26

JO - Journal of Micromechanics and Microengineering

JF - Journal of Micromechanics and Microengineering

IS - 7

M1 - 075014

ER -