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Role of Ser102 and Ser104 as Regulators of cGMP Hydrolysis by PDE5A
Julie Carøe Nordgaard, Lars Schack Kruse, Steen Gammeltoft,
Christina Kruuse
Institut for Klinisk Medicin
3
Citationer (Scopus)
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Medicine and Dentistry
Enzymatic Hydrolysis
100%
Cyclic GMP
100%
Migraine
75%
Phosphodiesterase
75%
Headache
50%
Calcitonin Gene Related Peptide
50%
Sildenafil
50%
Cilostazol
50%
Sumatriptan
50%
Glyceryl Trinitrate
50%
Signal Transduction
25%
Cell Extract
25%
Smooth Muscle Contraction
25%
Cytotechnology
25%
Cleft
25%
Green Fluorescent Protein
25%
Carboxy Terminal Sequence
25%
Allosteric Regulation
25%
Chimeric Protein
25%
Polyacrylamide Gel
25%
Cyclic Nucleotide
25%
In Vitro
25%
Vascular Smooth Muscle
25%
Phosphodiesterase V
25%
Neuroblastoma Cell
25%
Immunofluorescence
25%
Signaling Molecule
25%
Pharmacology, Toxicology and Pharmaceutical Science
Cyclic GMP
100%
Migraine
75%
Phosphodiesterase
75%
Calcitonin Gene Related Peptide
50%
Sildenafil
50%
Glyceryl Trinitrate
50%
Sumatriptan
50%
Cilostazol
50%
Headache
50%
Phosphodiesterase V
25%
Cyclic Nucleotide
25%
Polyacrylamide Gel
25%
Chimeric Protein
25%
Cell Extract
25%
Phosphoserine
25%
Green Fluorescent Protein
25%
Neuroblastoma
25%
Keyphrases
Cyclic GMP
100%
PDE5A
100%
Hydrolysis
100%
Sildenafil
13%
Headache
13%
Cilostazol
13%
Phosphodiesterase
13%
Glyceryl Trinitrate
13%
Double mutant
13%
Migraine Headache
13%
Calcitonin Gene-related Peptide
13%
Sumatriptan
13%
Doublet
6%
Phosphodiesterase Type 5 Inhibitors
6%
Phosphodiester Bond
6%
Intracellular Localization
6%
Intracellular Distribution
6%
Migraine-like
6%
Diverse Roles
6%
Vascular Dysfunction
6%
Immunofluorescence
6%
Cyclic nucleotides
6%
Green Fluorescent Protein
6%
Clinical Application
6%
Allosteric Regulation
6%
Enhanced Green Fluorescent Protein (eGFP)
6%
Neuroblastoma Cells
6%
In Vitro Assay
6%
Conformational Flexibility
6%
Neuronal Signaling
6%
Phosphorylation State
6%
Cell-free Extract
6%
Single Band
6%
Phosphodiesterase Activity
6%
Regulatory Mechanism
6%
Transfected Cells
6%
Fixed Cells
6%
Substitution mutation
6%
Cell Biology
6%
Terminal Fusion
6%
Phosphoserine
6%