Risk factors of pre-hypertension and hypertension among non-pregnant women of reproductive age in northeastern Tanzania: a community based cross-sectional study

TY - JOUR

T1 - Risk factors of pre-hypertension and hypertension among non-pregnant women of reproductive age in northeastern Tanzania

T2 - a community based cross-sectional study

AU - Msemo, Omari A.

AU - Schmiegelow, Christentze

AU - Nielsen, Birgitte B.

AU - Kousholt, Hannah

AU - Grunnet, Louise G.

AU - Christensen, Dirk L.

AU - Lusingu, John P.A.

AU - Møller, Sofie L.

AU - Kavishe, Reginald A.

AU - Minja, Daniel T.R.

AU - Bygbjerg, Ib C.

N1 - © 2018 John Wiley & Sons Ltd.

PY - 2018

Y1 - 2018

N2 - Objectives: To determine risk factors of pre-hypertension and hypertension in a cohort of 1247 rural Tanzanian women before conception. Methods: Demographic and socioeconomic data, anthropometric measurements, past medical and obstetric history and other risk factors for pre-hypertension and hypertension were collected using a structured questionnaire. Multiple logistic regression analysis was used to evaluate the associations between anthropometric indices and other risk factors of pre-hypertension and hypertension. The predictive power of different anthropometric indicators for identification of pre-hypertension and hypertension patients was determined by Receiver Operating Characteristic curves (ROC). Results: The median (range) age was 28.0 (18–40) years. The age-standardised prevalences of pre-hypertension and hypertension were 37.2 (95% CI 34.0–40.6) and 8.5% (95%CI 6.7–10.8), respectively. Of hypertensive patients (n = 98), only 20 (20.4%) were aware of their condition. In multivariate analysis, increasing age, obesity and haemoglobin levels were significantly associated with pre-hypertension and hypertension. Conclusion: Despite a low prevalence of hypertension, over one third of the women had pre-hypertension. This poses a great challenge ahead as pre-hypertensive women may progress into hypertension as they grow older without appropriate interventions. Obesity was the single most important modifiable risk factor for pre-hypertension and hypertension.

AB - Objectives: To determine risk factors of pre-hypertension and hypertension in a cohort of 1247 rural Tanzanian women before conception. Methods: Demographic and socioeconomic data, anthropometric measurements, past medical and obstetric history and other risk factors for pre-hypertension and hypertension were collected using a structured questionnaire. Multiple logistic regression analysis was used to evaluate the associations between anthropometric indices and other risk factors of pre-hypertension and hypertension. The predictive power of different anthropometric indicators for identification of pre-hypertension and hypertension patients was determined by Receiver Operating Characteristic curves (ROC). Results: The median (range) age was 28.0 (18–40) years. The age-standardised prevalences of pre-hypertension and hypertension were 37.2 (95% CI 34.0–40.6) and 8.5% (95%CI 6.7–10.8), respectively. Of hypertensive patients (n = 98), only 20 (20.4%) were aware of their condition. In multivariate analysis, increasing age, obesity and haemoglobin levels were significantly associated with pre-hypertension and hypertension. Conclusion: Despite a low prevalence of hypertension, over one third of the women had pre-hypertension. This poses a great challenge ahead as pre-hypertensive women may progress into hypertension as they grow older without appropriate interventions. Obesity was the single most important modifiable risk factor for pre-hypertension and hypertension.

KW - hypertension

KW - Pre-hypertension

KW - reproductive age

KW - Tanzania

KW - women

U2 - 10.1111/tmi.13149

DO - 10.1111/tmi.13149

M3 - Journal article

C2 - 30280462

AN - SCOPUS:85054327342

SN - 1360-2276

VL - 23

SP - 1176

EP - 1187

JO - Tropical Medicine & International Health

JF - Tropical Medicine & International Health

IS - 11

ER -