@article{d0552c304c7d11df928f000ea68e967b,
title = "Revised response criteria for malignant lymphoma",
abstract = "PURPOSE: Standardized response criteria are needed to interpret and compare clinical trials and for approval of new therapeutic agents by regulatory agencies. METHODS: The International Working Group response criteria (Cheson et al, J Clin Oncol 17:1244, 1999) were widely adopted, but required reassessment because of identified limitations and the increased use of [18F]fluorodeoxyglucose-positron emission tomography (PET), immunohistochemistry (IHC), and flow cytometry. The International Harmonization Project was convened to provide updated recommendations. RESULTS: New guidelines are presented incorporating PET, IHC, and flow cytometry for definitions of response in non-Hodgkin's and Hodgkin's lymphoma. Standardized definitions of end points are provided. CONCLUSION: We hope that these guidelines will be adopted widely by study groups, pharmaceutical and biotechnology companies, and regulatory agencies to facilitate the development of new and more effective therapies to improve the outcome of patients with lymphoma.",
author = "Cheson, {Bruce D} and Beate Pfistner and Juweid, {Malik E} and Gascoyne, {Randy D} and Lena Specht and Horning, {Sandra J} and Bertrand Coiffier and Fisher, {Richard I} and Anton Hagenbeek and Emanuele Zucca and Rosen, {Steven T} and Sigrid Stroobants and Lister, {T Andrew} and Hoppe, {Richard T} and Martin Dreyling and Kensei Tobinai and Vose, {Julie M} and Connors, {Joseph M} and Massimo Federico and Volker Diehl and Lena Specht",
note = "Keywords: Clinical Trials as Topic; Endpoint Determination; Flow Cytometry; Fluorodeoxyglucose F18; Hodgkin Disease; Humans; Image Interpretation, Computer-Assisted; Immunohistochemistry; Lymphoma, Non-Hodgkin; Positron-Emission Tomography; Radiopharmaceuticals; Survival Analysis; Terminology as Topic; Time Factors; Tomography, X-Ray Computed; Treatment Outcome",
year = "2007",
month = feb,
day = "10",
doi = "http://dx.doi.org/10.1200/JCO.2006.09.2403",
language = "English",
volume = "25",
pages = "579--86",
journal = "Journal of Clinical Oncology",
issn = "0732-183X",
publisher = "American Society of Clinical Oncology",
number = "5",
}