Reversal of rocuronium-induced neuromuscular block by the selective relaxant binding agent sugammadex: a dose-finding and safety study

Iben F Sorgenfrei; Kathrine Norrild; Per Bo Larsen; Jakob Stensballe; Doris Ostergaard; Martine E Prins; Jørgen Viby-Mogensen

Reversal of rocuronium-induced neuromuscular block by the selective relaxant binding agent sugammadex: a dose-finding and safety study

Iben F Sorgenfrei, Kathrine Norrild, Per Bo Larsen, Jakob Stensballe, Doris Ostergaard, Martine E Prins, Jørgen Viby-Mogensen

256 Citationer (Scopus)

Abstract

Sugammadex (Org 25969) forms a complex with steroidal neuromuscular blocking agents, thereby reversing neuromuscular block. This study investigated the dose-response relation, safety, and pharmacokinetics of sugammadex to reverse rocuronium-induced block.

Originalsprog	Engelsk
Tidsskrift	Anesthesiology
Vol/bind	104
Udgave nummer	4
Sider (fra-til)	667-74
Antal sider	8
ISSN	0003-3022
Status	Udgivet - 1 apr. 2006

Citationsformater

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title = "Reversal of rocuronium-induced neuromuscular block by the selective relaxant binding agent sugammadex: a dose-finding and safety study",

abstract = "Sugammadex (Org 25969) forms a complex with steroidal neuromuscular blocking agents, thereby reversing neuromuscular block. This study investigated the dose-response relation, safety, and pharmacokinetics of sugammadex to reverse rocuronium-induced block.",

author = "Sorgenfrei, {Iben F} and Kathrine Norrild and Larsen, {Per Bo} and Jakob Stensballe and Doris Ostergaard and Prins, {Martine E} and J{\o}rgen Viby-Mogensen",

year = "2006",

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language = "English",

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journal = "Anesthesiology",

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TY - JOUR

T1 - Reversal of rocuronium-induced neuromuscular block by the selective relaxant binding agent sugammadex: a dose-finding and safety study

AU - Sorgenfrei, Iben F

AU - Norrild, Kathrine

AU - Larsen, Per Bo

AU - Stensballe, Jakob

AU - Ostergaard, Doris

AU - Prins, Martine E

AU - Viby-Mogensen, Jørgen

PY - 2006/4/1

Y1 - 2006/4/1

N2 - Sugammadex (Org 25969) forms a complex with steroidal neuromuscular blocking agents, thereby reversing neuromuscular block. This study investigated the dose-response relation, safety, and pharmacokinetics of sugammadex to reverse rocuronium-induced block.

AB - Sugammadex (Org 25969) forms a complex with steroidal neuromuscular blocking agents, thereby reversing neuromuscular block. This study investigated the dose-response relation, safety, and pharmacokinetics of sugammadex to reverse rocuronium-induced block.

M3 - Journal article

SN - 0003-3022

VL - 104

SP - 667

EP - 674

JO - Anesthesiology

JF - Anesthesiology

IS - 4

ER -

Reversal of rocuronium-induced neuromuscular block by the selective relaxant binding agent sugammadex: a dose-finding and safety study

Abstract

Fingeraftryk

Citationsformater