TY - GEN
T1 - Results of the 2011 Relationship Testing Workshop of the English Speaking Working Group
AU - Poulsen, Lena
AU - Friis, Susanne Lunøe
AU - Hallenberg, Charlotte
AU - Simonsen, Bo Thisted
AU - Morling, Niels
PY - 2011/12
Y1 - 2011/12
N2 - We present the results of the 2011 Relationship Testing Workshop of the English Speaking Working Group of the International Society for Forensic Genetics. A total of 62 laboratories participated. The exercise included relationship testing of blood samples from a man and two children. Assuming that the man is the biological father of both children, the laboratories were asked to investigate if the results were in favour or against that the children were half or full siblings. Furthermore, the laboratories filled out a questionnaire concerning the laboratory strategies and routines. Finally, the laboratories were encouraged to do a paper challenge with statistical calculations. The relationship testing exercise revealed that the use of mtDNA and X-STR was informative and excluded the possibility of full siblings. In the questionnaire, most laboratories (77%) indicated that a single autosomal STR kit was used in all paternity cases. However, >60% of the laboratories had three or more autosomal STR kits available for paternity testing. The paper challenge showed large variations in the biostatistical calculations in cases of rare events such as a rare allele and when a single genetic inconsistency was observed.
AB - We present the results of the 2011 Relationship Testing Workshop of the English Speaking Working Group of the International Society for Forensic Genetics. A total of 62 laboratories participated. The exercise included relationship testing of blood samples from a man and two children. Assuming that the man is the biological father of both children, the laboratories were asked to investigate if the results were in favour or against that the children were half or full siblings. Furthermore, the laboratories filled out a questionnaire concerning the laboratory strategies and routines. Finally, the laboratories were encouraged to do a paper challenge with statistical calculations. The relationship testing exercise revealed that the use of mtDNA and X-STR was informative and excluded the possibility of full siblings. In the questionnaire, most laboratories (77%) indicated that a single autosomal STR kit was used in all paternity cases. However, >60% of the laboratories had three or more autosomal STR kits available for paternity testing. The paper challenge showed large variations in the biostatistical calculations in cases of rare events such as a rare allele and when a single genetic inconsistency was observed.
M3 - Conference article
SN - 1875-1768
VL - 3
SP - e512-e513
JO - Forensic Science International: Genetics. Supplement Series
JF - Forensic Science International: Genetics. Supplement Series
ER -