Results for five sets of forensic genetic markers studied in a Greek population sample

TY - JOUR

T1 - Results for five sets of forensic genetic markers studied in a Greek population sample

AU - Tomas Mas, Carmen

AU - Skitsa, I

AU - Steinmeier, E

AU - Poulsen, Lena

AU - Ampati, A

AU - Børsting, Claus

AU - Morling, N

N1 - Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

PY - 2015/5

Y1 - 2015/5

N2 - A population sample of 223 Greek individuals was typed for five sets of forensic genetic markers with the kits NGM SElect™, SNPforID 49plex, DIPplex®, Argus X-12 and PowerPlex® Y23. No significant deviation from Hardy-Weinberg expectations was observed for any of the studied markers after Holm-Šidák correction. Statistically significant (P < 0.05) levels of linkage disequilibrium were observed between markers within two of the studied X-chromosome linkage groups. AMOVA analyses of the five sets of markers did not show population structure when the individuals were grouped according to their geographic origin. The Greek population grouped closely to the other European populations measured by FST∗ distances. The match probability ranged from a value of 1 in 2 × 107 males by using haplotype frequencies of four X-chromosome haplogroups in males to 1 in 1.73 × 1021 individuals for 16 autosomal STRs.

AB - A population sample of 223 Greek individuals was typed for five sets of forensic genetic markers with the kits NGM SElect™, SNPforID 49plex, DIPplex®, Argus X-12 and PowerPlex® Y23. No significant deviation from Hardy-Weinberg expectations was observed for any of the studied markers after Holm-Šidák correction. Statistically significant (P < 0.05) levels of linkage disequilibrium were observed between markers within two of the studied X-chromosome linkage groups. AMOVA analyses of the five sets of markers did not show population structure when the individuals were grouped according to their geographic origin. The Greek population grouped closely to the other European populations measured by FST∗ distances. The match probability ranged from a value of 1 in 2 × 107 males by using haplotype frequencies of four X-chromosome haplogroups in males to 1 in 1.73 × 1021 individuals for 16 autosomal STRs.

U2 - 10.1016/j.fsigen.2015.01.001

DO - 10.1016/j.fsigen.2015.01.001

M3 - Letter

C2 - 25600395

SN - 1872-4973

VL - 16

SP - 132

EP - 137

JO - Forensic Science International: Genetics

JF - Forensic Science International: Genetics

ER -