Resistance training in patients with limb-girdle and becker muscular dystrophies

Marie-Louise Sveen; Søren P Andersen; Lina H Ingelsrud; Sarah Blichter; Niels E Olsen; Simon Jønck; Thomas O Krag; John Vissing

doi:10.1002/mus.23491

Resistance training in patients with limb-girdle and becker muscular dystrophies

Marie-Louise Sveen, Søren P Andersen, Lina H Ingelsrud, Sarah Blichter, Niels E Olsen, Simon Jønck, Thomas O Krag, John Vissing

31 Citationer (Scopus)

Abstract

Introduction: In this study we investigated the effect of strength training in patients with limb-girdle muscular dystrophy (LGMD) and Becker muscular dystrophy (BMD). Methods: In 2 studies we compared the effect of low-intensity training (LOIT; n = 8) and high-intensity training (HIT; n = 4) in muscles of the upper and lower extremities. Patients were tested for maximal strength and endurance before and after the training program. Results: LOIT training over 6 months resulted in increased biceps strength and endurance. HIT training increased endurance and strength in wrist flexion and extension and in elbow flexion. One patient discontinued HIT training due to muscle soreness and mildly increased plasma CK levels without strength deterioration. Conclusions: Both LOIT and HIT increased muscle strength and endurance in some of the muscles tested and were well tolerated in most patients. Our findings suggest that supervised resistance training may be considered in the management of patients with LGMD2 and BMD.

Originalsprog	Engelsk
Tidsskrift	Muscle & Nerve
Vol/bind	47
Udgave nummer	2
Sider (fra-til)	163-9
Antal sider	7
ISSN	0148-639X
DOI	https://doi.org/10.1002/mus.23491
Status	Udgivet - feb. 2013

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10.1002/mus.23491

Citationsformater

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title = "Resistance training in patients with limb-girdle and becker muscular dystrophies",

abstract = "Introduction: In this study we investigated the effect of strength training in patients with limb-girdle muscular dystrophy (LGMD) and Becker muscular dystrophy (BMD). Methods: In 2 studies we compared the effect of low-intensity training (LOIT; n = 8) and high-intensity training (HIT; n = 4) in muscles of the upper and lower extremities. Patients were tested for maximal strength and endurance before and after the training program. Results: LOIT training over 6 months resulted in increased biceps strength and endurance. HIT training increased endurance and strength in wrist flexion and extension and in elbow flexion. One patient discontinued HIT training due to muscle soreness and mildly increased plasma CK levels without strength deterioration. Conclusions: Both LOIT and HIT increased muscle strength and endurance in some of the muscles tested and were well tolerated in most patients. Our findings suggest that supervised resistance training may be considered in the management of patients with LGMD2 and BMD.",

author = "Marie-Louise Sveen and Andersen, {S{\o}ren P} and Ingelsrud, {Lina H} and Sarah Blichter and Olsen, {Niels E} and Simon J{\o}nck and Krag, {Thomas O} and John Vissing",

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year = "2013",

month = feb,

doi = "10.1002/mus.23491",

language = "English",

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TY - JOUR

T1 - Resistance training in patients with limb-girdle and becker muscular dystrophies

AU - Sveen, Marie-Louise

AU - Andersen, Søren P

AU - Ingelsrud, Lina H

AU - Blichter, Sarah

AU - Olsen, Niels E

AU - Jønck, Simon

AU - Krag, Thomas O

AU - Vissing, John

PY - 2013/2

Y1 - 2013/2

N2 - Introduction: In this study we investigated the effect of strength training in patients with limb-girdle muscular dystrophy (LGMD) and Becker muscular dystrophy (BMD). Methods: In 2 studies we compared the effect of low-intensity training (LOIT; n = 8) and high-intensity training (HIT; n = 4) in muscles of the upper and lower extremities. Patients were tested for maximal strength and endurance before and after the training program. Results: LOIT training over 6 months resulted in increased biceps strength and endurance. HIT training increased endurance and strength in wrist flexion and extension and in elbow flexion. One patient discontinued HIT training due to muscle soreness and mildly increased plasma CK levels without strength deterioration. Conclusions: Both LOIT and HIT increased muscle strength and endurance in some of the muscles tested and were well tolerated in most patients. Our findings suggest that supervised resistance training may be considered in the management of patients with LGMD2 and BMD.

AB - Introduction: In this study we investigated the effect of strength training in patients with limb-girdle muscular dystrophy (LGMD) and Becker muscular dystrophy (BMD). Methods: In 2 studies we compared the effect of low-intensity training (LOIT; n = 8) and high-intensity training (HIT; n = 4) in muscles of the upper and lower extremities. Patients were tested for maximal strength and endurance before and after the training program. Results: LOIT training over 6 months resulted in increased biceps strength and endurance. HIT training increased endurance and strength in wrist flexion and extension and in elbow flexion. One patient discontinued HIT training due to muscle soreness and mildly increased plasma CK levels without strength deterioration. Conclusions: Both LOIT and HIT increased muscle strength and endurance in some of the muscles tested and were well tolerated in most patients. Our findings suggest that supervised resistance training may be considered in the management of patients with LGMD2 and BMD.

U2 - 10.1002/mus.23491

DO - 10.1002/mus.23491

M3 - Journal article

C2 - 23169433

SN - 0148-639X

VL - 47

SP - 163

EP - 169

JO - Muscle & Nerve

JF - Muscle & Nerve

IS - 2

ER -

Resistance training in patients with limb-girdle and becker muscular dystrophies

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