Renal myoglobin in drug addicts: occurrence and significance in a postmortem study

Kirsten Friis Kock; Kirsten Wiese Simonsen

doi:10.1016/0379-0738(94)90266-6

Renal myoglobin in drug addicts: occurrence and significance in a postmortem study

Kirsten Friis Kock, Kirsten Wiese Simonsen

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Abstract

In a 3-year period (1989–1991) a non-selected, consecutive series of 62 deaths in drug addicts was autopsied at the Forensic Institute in Odense. The kidney sections from these addicts were examined for the presence of renal myoglobin using immunohistochemical methods. A reference group consisting of a non-selected, non-consecutive series of 58 autopsied nonaddicts was likewise investigated for the presence of renal myoglobin. No major differences were demonstrated between the two groups. The presence of renal myoglobin probably indicates a prolonged course of events prior to death (unconsciousness, immobilization, hypovolemia). In sufficient amounts, renal myoglobin may be of importance as a cause of death or a contributing factor to death in both drug addicts and non-addicts.

Originalsprog	Engelsk
Tidsskrift	Forensic Science International
Vol/bind	65
Udgave nummer	2
Sider (fra-til)	113-119
Antal sider	7
ISSN	0379-0738
DOI	https://doi.org/10.1016/0379-0738(94)90266-6
Status	Udgivet - 25 mar. 1994

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@article{2ae405df93b04147aca5b1ca69b4955a,

title = "Renal myoglobin in drug addicts: occurrence and significance in a postmortem study",

abstract = "In a 3-year period (1989–1991) a non-selected, consecutive series of 62 deaths in drug addicts was autopsied at the Forensic Institute in Odense. The kidney sections from these addicts were examined for the presence of renal myoglobin using immunohistochemical methods. A reference group consisting of a non-selected, non-consecutive series of 58 autopsied nonaddicts was likewise investigated for the presence of renal myoglobin. No major differences were demonstrated between the two groups. The presence of renal myoglobin probably indicates a prolonged course of events prior to death (unconsciousness, immobilization, hypovolemia). In sufficient amounts, renal myoglobin may be of importance as a cause of death or a contributing factor to death in both drug addicts and non-addicts. ",

keywords = "Faculty of Health and Medical Sciences, Myoglobin, Renal Failure, addiction",

author = "Kock, {Kirsten Friis} and Simonsen, {Kirsten Wiese}",

year = "1994",

month = mar,

day = "25",

doi = "10.1016/0379-0738(94)90266-6",

language = "English",

volume = "65",

pages = "113--119",

journal = "Forensic Science International",

issn = "0379-0738",

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}

TY - JOUR

T1 - Renal myoglobin in drug addicts: occurrence and significance in a postmortem study

AU - Kock, Kirsten Friis

AU - Simonsen, Kirsten Wiese

PY - 1994/3/25

Y1 - 1994/3/25

N2 - In a 3-year period (1989–1991) a non-selected, consecutive series of 62 deaths in drug addicts was autopsied at the Forensic Institute in Odense. The kidney sections from these addicts were examined for the presence of renal myoglobin using immunohistochemical methods. A reference group consisting of a non-selected, non-consecutive series of 58 autopsied nonaddicts was likewise investigated for the presence of renal myoglobin. No major differences were demonstrated between the two groups. The presence of renal myoglobin probably indicates a prolonged course of events prior to death (unconsciousness, immobilization, hypovolemia). In sufficient amounts, renal myoglobin may be of importance as a cause of death or a contributing factor to death in both drug addicts and non-addicts.

AB - In a 3-year period (1989–1991) a non-selected, consecutive series of 62 deaths in drug addicts was autopsied at the Forensic Institute in Odense. The kidney sections from these addicts were examined for the presence of renal myoglobin using immunohistochemical methods. A reference group consisting of a non-selected, non-consecutive series of 58 autopsied nonaddicts was likewise investigated for the presence of renal myoglobin. No major differences were demonstrated between the two groups. The presence of renal myoglobin probably indicates a prolonged course of events prior to death (unconsciousness, immobilization, hypovolemia). In sufficient amounts, renal myoglobin may be of importance as a cause of death or a contributing factor to death in both drug addicts and non-addicts.

KW - Faculty of Health and Medical Sciences

KW - Myoglobin

KW - Renal Failure

KW - addiction

U2 - 10.1016/0379-0738(94)90266-6

DO - 10.1016/0379-0738(94)90266-6

M3 - Journal article

SN - 0379-0738

VL - 65

SP - 113

EP - 119

JO - Forensic Science International

JF - Forensic Science International

IS - 2

ER -

Renal myoglobin in drug addicts: occurrence and significance in a postmortem study

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