Regional cerebral blood flow during rest and skilled hand movements by Xenon-133 inhalation and emission computerized tomography

TY - JOUR

T1 - Regional cerebral blood flow during rest and skilled hand movements by Xenon-133 inhalation and emission computerized tomography

AU - Lauritzen, M.

AU - Henriksen, L.

AU - Lassen, N. A.

PY - 1981/1/1

Y1 - 1981/1/1

N2 - Regional cerebral blood flow (CBF) was studied in 16 normal adult volunteers during rest and in 10 the study was repeated during skilled hand movements. A fast-rotating ('dynamic'), single-photon emission computerized tomograph (ECT) with four detector heads was used. Xenon-133 was inhaled over a 1-min period at a concentration of 10 mCi/L. The arrival and washout of the radioisotope was recorded during four 1-min periods. Two slices, 2 cm thick, 7 and 12 cm above the orbitomeatal line were obtained in every study. CBF averaged 60 ml/100/g/min (SD ± 11) in the lower slice and 51 ml/100/g/min (SD ± 13) in the upper slice. A symmetric pattern comparing right to left sides was found in both slices. Finger tapping and writing with the right hand increased CBF in specific areas of the upper slice: in the contralateral hand area by 35 ± 15% (p<0.025), and in the supplementary motor area on both sides by 34 ± 15% (p<0.025).

AB - Regional cerebral blood flow (CBF) was studied in 16 normal adult volunteers during rest and in 10 the study was repeated during skilled hand movements. A fast-rotating ('dynamic'), single-photon emission computerized tomograph (ECT) with four detector heads was used. Xenon-133 was inhaled over a 1-min period at a concentration of 10 mCi/L. The arrival and washout of the radioisotope was recorded during four 1-min periods. Two slices, 2 cm thick, 7 and 12 cm above the orbitomeatal line were obtained in every study. CBF averaged 60 ml/100/g/min (SD ± 11) in the lower slice and 51 ml/100/g/min (SD ± 13) in the upper slice. A symmetric pattern comparing right to left sides was found in both slices. Finger tapping and writing with the right hand increased CBF in specific areas of the upper slice: in the contralateral hand area by 35 ± 15% (p<0.025), and in the supplementary motor area on both sides by 34 ± 15% (p<0.025).

UR - http://www.scopus.com/inward/record.url?scp=0019853772&partnerID=8YFLogxK

U2 - 10.1038/jcbfm.1981.42

DO - 10.1038/jcbfm.1981.42

M3 - Journal article

C2 - 6976975

AN - SCOPUS:0019853772

SN - 0271-678X

VL - 1

SP - 385

EP - 389

JO - Journal of Cerebral Blood Flow and Metabolism

JF - Journal of Cerebral Blood Flow and Metabolism

IS - 4

ER -