Proportion of ovine pulmonary adenocarcinoma in Danish sheep at slaughter.

Cathrine  Erichsen; Chris Cousen; Jeanie Finlayson; Madeleine Maley; Mark Dagleish; Søren Saxmose Nielsen

Proportion of ovine pulmonary adenocarcinoma in Danish sheep at slaughter.

Cathrine Erichsen, Chris Cousen, Jeanie Finlayson, Madeleine Maley, Mark Dagleish, Søren Saxmose Nielsen

24 Downloads (Pure)

Abstract

Ovine pulmonary adenocarcinoma (OPA) is prevalent in many sheep producing countries such as the United Kingdom, but the prevalence of OPA is not known in Denmark, where sheep production is less intensive. Our objective was to estimate the proportion of OPA in Danish sheep at slaughter. All adult sheep (n=235) and lambs (n=1245) slaughtered at the largest Danish sheep abattoir, receiving animals from the entire country, were collected from 29th February to 25th April 2016 in a cross-sectional-like study. A total of 1480 pairs of lungs from lambs and adult sheep were examined visually and by palpation. Based on gross examination, 25 animals were suspected to have OPA and were examined in more detail by histology and immunohistochemistry. None had OPA. This is in contrast to previous incidental findings of OPA at two farms in 2014. Based on the sample size of adult sheep examined, the prevalence should not exceed 1.3% if the samples collected were representative of the Danish sheep population. However, for greater accuracy, larger studies would be required if the prevalence is 1-2% or less. The study also highlights the necessity for histological examination for definitive diagnosis when undertaking studies on the prevalence of OPA and other lung diseases.

Originalsprog	Engelsk
Tidsskrift	Dansk Veterinaertidsskrift
Vol/bind	2018
Udgave nummer	10
Sider (fra-til)	30-34
Antal sider	5
ISSN	0106-6854
Status	Udgivet - 2018

Adgang til dokumentet

Erichsen_Cousens_Finlayson_Maley_Dagleish_Nielsen_2018Forlagets udgivne version, 3,63 MB

Citationsformater

@article{f6a638e7b0ae4ee09f11f7474bdc522b,

title = "Proportion of ovine pulmonary adenocarcinoma in Danish sheep at slaughter.",

abstract = "Ovine pulmonary adenocarcinoma (OPA) is prevalent in many sheep producing countries such as the United Kingdom, but the prevalence of OPA is not known in Denmark, where sheep production is less intensive. Our objective was to estimate the proportion of OPA in Danish sheep at slaughter. All adult sheep (n=235) and lambs (n=1245) slaughtered at the largest Danish sheep abattoir, receiving animals from the entire country, were collected from 29th February to 25th April 2016 in a cross-sectional-like study. A total of 1480 pairs of lungs from lambs and adult sheep were examined visually and by palpation. Based on gross examination, 25 animals were suspected to have OPA and were examined in more detail by histology and immunohistochemistry. None had OPA. This is in contrast to previous incidental findings of OPA at two farms in 2014. Based on the sample size of adult sheep examined, the prevalence should not exceed 1.3% if the samples collected were representative of the Danish sheep population. However, for greater accuracy, larger studies would be required if the prevalence is 1-2% or less. The study also highlights the necessity for histological examination for definitive diagnosis when undertaking studies on the prevalence of OPA and other lung diseases.",

author = "Cathrine Erichsen and Chris Cousen and Jeanie Finlayson and Madeleine Maley and Mark Dagleish and Nielsen, {S{\o}ren Saxmose}",

year = "2018",

language = "English",

volume = "2018",

pages = "30--34",

journal = "Dansk Veterinaertidsskrift",

issn = "0106-6854",

publisher = "Den Danske Dyrl{\ae}geforening",

number = "10",

}

TY - JOUR

T1 - Proportion of ovine pulmonary adenocarcinoma in Danish sheep at slaughter.

AU - Erichsen, Cathrine

AU - Cousen, Chris

AU - Finlayson, Jeanie

AU - Maley, Madeleine

AU - Dagleish, Mark

AU - Nielsen, Søren Saxmose

PY - 2018

Y1 - 2018

N2 - Ovine pulmonary adenocarcinoma (OPA) is prevalent in many sheep producing countries such as the United Kingdom, but the prevalence of OPA is not known in Denmark, where sheep production is less intensive. Our objective was to estimate the proportion of OPA in Danish sheep at slaughter. All adult sheep (n=235) and lambs (n=1245) slaughtered at the largest Danish sheep abattoir, receiving animals from the entire country, were collected from 29th February to 25th April 2016 in a cross-sectional-like study. A total of 1480 pairs of lungs from lambs and adult sheep were examined visually and by palpation. Based on gross examination, 25 animals were suspected to have OPA and were examined in more detail by histology and immunohistochemistry. None had OPA. This is in contrast to previous incidental findings of OPA at two farms in 2014. Based on the sample size of adult sheep examined, the prevalence should not exceed 1.3% if the samples collected were representative of the Danish sheep population. However, for greater accuracy, larger studies would be required if the prevalence is 1-2% or less. The study also highlights the necessity for histological examination for definitive diagnosis when undertaking studies on the prevalence of OPA and other lung diseases.

AB - Ovine pulmonary adenocarcinoma (OPA) is prevalent in many sheep producing countries such as the United Kingdom, but the prevalence of OPA is not known in Denmark, where sheep production is less intensive. Our objective was to estimate the proportion of OPA in Danish sheep at slaughter. All adult sheep (n=235) and lambs (n=1245) slaughtered at the largest Danish sheep abattoir, receiving animals from the entire country, were collected from 29th February to 25th April 2016 in a cross-sectional-like study. A total of 1480 pairs of lungs from lambs and adult sheep were examined visually and by palpation. Based on gross examination, 25 animals were suspected to have OPA and were examined in more detail by histology and immunohistochemistry. None had OPA. This is in contrast to previous incidental findings of OPA at two farms in 2014. Based on the sample size of adult sheep examined, the prevalence should not exceed 1.3% if the samples collected were representative of the Danish sheep population. However, for greater accuracy, larger studies would be required if the prevalence is 1-2% or less. The study also highlights the necessity for histological examination for definitive diagnosis when undertaking studies on the prevalence of OPA and other lung diseases.

M3 - Journal article

SN - 0106-6854

VL - 2018

SP - 30

EP - 34

JO - Dansk Veterinaertidsskrift

JF - Dansk Veterinaertidsskrift

IS - 10

ER -

Proportion of ovine pulmonary adenocarcinoma in Danish sheep at slaughter.

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater