PRODRUGS OF NAPROXEN AND DICLOFENAC

Claus Selch Larsen (Opfinder), Susan Weng Larsen (Opfinder), Mette Agergaard Thing (Opfinder), Jesper Langgaard Kristensen (Opfinder), HENRIK JENSEN (Opfinder), JESPER ØSTERGAARD (Opfinder)

    Abstract

    The present invention relates to a compound of formula (I): wherein R1 is R3-IPU and R2 is the acyloxy residue of diclofenac or naproxen, and specified by the following structures (A) wherein OH—R3-IPU is selected from (B) and R4 and R5 may be the same or different selected from (C) and salts, solvates and hydrates thereof.

    OriginalsprogEngelsk
    IPCA61K 45/ 06 A I
    PatentnummerUS2016074523
    Land/OmrådeDanmark
    Prioritetsdato28/04/2014
    PrioritetsnummerWO2014EP58530
    StatusUdgivet - 17 mar. 2016

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