Prenatal characteristics of false negative cases from first-trimester screening of Down syndrome (trisomy 21)

TY - JOUR

T1 - Prenatal characteristics of false negative cases from first-trimester screening of Down syndrome (trisomy 21)

AU - Simonsen, Tanja Schlaikjær

AU - Sørensen, Steen

AU - Ekelund, Charlotte

AU - Jørgensen, Finn Stener

AU - Danish Fetal Medicine Research Group

AU - Andersen, Hans Jakob

AU - Christensen, Jeanette

AU - Ersbak, Vibeke

AU - Petersen, Olav Bennike Bjørn

AU - Sundberg, Karin

AU - Tabor, Ann

AU - Zingenberg, Helle Jeanette

PY - 2013/4

Y1 - 2013/4

N2 - What's already known about this topic? In DS cases, maternal age, NT and hCGβ (multiples of median) are high, whereas PAPP-A (multiples of median) is low. What does this study add? This study describes in details the distribution of maternal age, NT, crown rump length and biochemical markers of false negative cases from the first-trimester combined screening for DS.

AB - What's already known about this topic? In DS cases, maternal age, NT and hCGβ (multiples of median) are high, whereas PAPP-A (multiples of median) is low. What does this study add? This study describes in details the distribution of maternal age, NT, crown rump length and biochemical markers of false negative cases from the first-trimester combined screening for DS.

U2 - 10.1002/pd.4081

DO - 10.1002/pd.4081

M3 - Journal article

C2 - 23553404

SN - 0197-3851

VL - 33

SP - 400

EP - 402

JO - Prenatal Diagnosis

JF - Prenatal Diagnosis

IS - 4

ER -