TY - JOUR
T1 - Preliminary study of dengue virus infection in Iran
AU - Chinikar, Sadegh
AU - Ghiasi, Seyed Mojtaba
AU - Shah-Hosseini, Nariman
AU - Mostafavi, Ehsan
AU - Moradi, Maryam
AU - Khakifirouz, Sahar
AU - Rasi Varai, Fereshteh Sadat
AU - Rafigh, Mahboubeh
AU - Jalali, Tahmineh
AU - Goya, Mohammad Mehdi
AU - Shirzadi, Mohammad Reza
AU - Zainali, Mohammad
AU - Fooks, Anthony R
N1 - Copyright © 2012 Elsevier Ltd. All rights reserved.
PY - 2013/5
Y1 - 2013/5
N2 - Dengue fever is one of the most important arthropod-borne viral diseases of public health significance. It is endemic in most tropical and subtropical parts of the world, many of which are popular tourist destinations. The presence of dengue infection was examined in Iranian patients who were referred to the Arboviruses and Viral Haemorrhagic Fevers Laboratory of the Pasteur Institute of Iran and tested negative for Crimean-Congo Haemorrhagic Fever (CCHF) between 2000 and 2012. Serum samples from these patients were tested for the presence of specific IgG and IgM and viral nucleic acid in blood. Of the 300 sera tested, 15 (5%) were seropositive, and 3 (1%) were both serologically and PCR positive. Of the 15 seropositive cases, 8 (53.3%) had travelled to endemic areas including Malaysia (5, 62.5%), India (2, 25%) and Thailand (1, 12.5%). In contrast, 7 (46.7%) of the cases had not reported travelling abroad. Of these, six cases were from the Sistan and Baluchistan province in southeast Iran and neighbouring Pakistan. Travellers play a key role in the epidemiology of dengue infection in Iran and it is recommended that travellers to endemic areas take precautionary measures to avoid mosquito bites.
AB - Dengue fever is one of the most important arthropod-borne viral diseases of public health significance. It is endemic in most tropical and subtropical parts of the world, many of which are popular tourist destinations. The presence of dengue infection was examined in Iranian patients who were referred to the Arboviruses and Viral Haemorrhagic Fevers Laboratory of the Pasteur Institute of Iran and tested negative for Crimean-Congo Haemorrhagic Fever (CCHF) between 2000 and 2012. Serum samples from these patients were tested for the presence of specific IgG and IgM and viral nucleic acid in blood. Of the 300 sera tested, 15 (5%) were seropositive, and 3 (1%) were both serologically and PCR positive. Of the 15 seropositive cases, 8 (53.3%) had travelled to endemic areas including Malaysia (5, 62.5%), India (2, 25%) and Thailand (1, 12.5%). In contrast, 7 (46.7%) of the cases had not reported travelling abroad. Of these, six cases were from the Sistan and Baluchistan province in southeast Iran and neighbouring Pakistan. Travellers play a key role in the epidemiology of dengue infection in Iran and it is recommended that travellers to endemic areas take precautionary measures to avoid mosquito bites.
KW - Adult
KW - Aged
KW - Antibodies, Viral
KW - Dengue
KW - Dengue Virus
KW - Female
KW - Hemorrhagic Fever, Crimean
KW - Humans
KW - Iran
KW - Male
KW - Middle Aged
KW - Public Health Surveillance
KW - Retrospective Studies
KW - Travel Medicine
U2 - 10.1016/j.tmaid.2012.10.001
DO - 10.1016/j.tmaid.2012.10.001
M3 - Journal article
C2 - 23194952
SN - 1477-8939
VL - 11
SP - 166
EP - 169
JO - Travel Medicine and Infectious Disease
JF - Travel Medicine and Infectious Disease
IS - 3
ER -
