TY - JOUR
T1 - Preferences for prenatal tests for Down syndrome
T2 - An international comparison of the views of pregnant women and health professionals
AU - Hill, Melissa
AU - Johnson, Jo Ann
AU - Langlois, Sylvie
AU - Lee, Hyun
AU - Winsor, Stephanie
AU - Dineley, Brigid
AU - Horniachek, Marisa
AU - Lalatta, Faustina
AU - Ronzoni, Luisa
AU - Barrett, Angela N.
AU - Advani, Henna V.
AU - Choolani, Mahesh
AU - Rabinowitz, Ron
AU - Pajkrt, Eva
AU - Van Schendel, Rachèl V.
AU - Henneman, Lidewij
AU - Rommers, Wieke
AU - Bilardo, Caterina M.
AU - Rendeiro, Paula
AU - Ribeiro, Maria João
AU - Rocha, José
AU - Bay Lund, Ida Charlotte
AU - Petersen, Olav B.
AU - Becher, Naja
AU - Vogel, Ida
AU - Stefánsdottir, Vigdis
AU - Ingvarsdottir, Sigrun
AU - Gottfredsdottir, Helga
AU - Morris, Stephen
AU - Chitty, Lyn S.
PY - 2016
Y1 - 2016
N2 - Non-invasive prenatal testing is increasingly available worldwide and stakeholder viewpoints are essential to guide implementation. Here we compare the preferences of women and health professionals from nine different countries towards attributes of non-invasive and invasive prenatal tests for Down syndrome. A discrete choice experiment was used to obtain participants' stated preference for prenatal tests that varied according to four attributes: accuracy, time of test, risk of miscarriage, and type of information. Pregnant women and health professionals were recruited from Canada, Denmark, Iceland, Israel, Italy, the Netherlands, Portugal, Singapore, and the United Kingdom. A total of 2666 women's and 1245 health professionals' questionnaires were included in the analysis. Differences in preferences were seen between women and health professionals within and between countries. Overall, women placed greater emphasis on test safety and comprehensive information than health professionals, who emphasised accuracy and early testing. Differences between women's and health professionals' preferences are marked between countries. Varied approaches to implementation and service delivery are therefore needed and individual countries should develop guidelines appropriate for their own social and screening contexts.
AB - Non-invasive prenatal testing is increasingly available worldwide and stakeholder viewpoints are essential to guide implementation. Here we compare the preferences of women and health professionals from nine different countries towards attributes of non-invasive and invasive prenatal tests for Down syndrome. A discrete choice experiment was used to obtain participants' stated preference for prenatal tests that varied according to four attributes: accuracy, time of test, risk of miscarriage, and type of information. Pregnant women and health professionals were recruited from Canada, Denmark, Iceland, Israel, Italy, the Netherlands, Portugal, Singapore, and the United Kingdom. A total of 2666 women's and 1245 health professionals' questionnaires were included in the analysis. Differences in preferences were seen between women and health professionals within and between countries. Overall, women placed greater emphasis on test safety and comprehensive information than health professionals, who emphasised accuracy and early testing. Differences between women's and health professionals' preferences are marked between countries. Varied approaches to implementation and service delivery are therefore needed and individual countries should develop guidelines appropriate for their own social and screening contexts.
U2 - 10.1038/ejhg.2015.249
DO - 10.1038/ejhg.2015.249
M3 - Journal article
C2 - 26577044
AN - SCOPUS:84947551762
SN - 1018-4813
VL - 24
SP - 968
EP - 975
JO - European Journal of Human Genetics
JF - European Journal of Human Genetics
ER -