Praeoperativt delay hos patienter med perforeret ulcus: en klinisk audit fra Det Nationale Indikatorprojekt

Morten Hylander Møller, Bente Mertz Nørgård, Frank Mehnert, Jørgen Bendix, Ann-Sophie Nielsen, Anne Nakano, Sven Adamsen, Reimar Wernich Thomsen, Morten Hylander Møller, Bente Mertz Nørgård, Frank Mehnert, Jørgen Bendix, Ann-Sophie Nielsen, Anne Nakano Jensen, Sven Adamsen, Reimar Wernich Thomsen

    Abstract

    INTRODUCTION: Mortality following perforated peptic ulcer in Denmark is nearly 30%. Delayed surgery is a prognostic factor, but only half of the patients are operated within six hours of perforation - a predefined quality of care criterion in The Danish National Indicator Project. A clinical audit was conducted to investigate possible reasons. MATERIAL AND METHODS: All patients (n = 89) surgically treated for peptic ulcer perforation in six university hospitals in Denmark over a period of one year were included. The association between a number of predefined variables related to the internal organisation of health care, the patient's pathological picture and the quality of treatment given, and a preoperative delay of at least 6 hours was examined using modified Poisson regression analyses. RESULTS: The following variables were associated with a preoperative delay = 6 hours: 1) out of hospital versus in hospital perforation (adjusted relative risk (RR) 1.87; 95% confidence interval (CI) 0.86-4.05), 2) no classical clinical symptoms of ulcer perforation (adjusted RR with peritonism 0.32; 95% CI 0.14-0.73), 3) first physician attendance later than median time, i.e. > 25 minutes after debut (adjusted RR 2.78; 95% CI 1.32-5.87), 4) first attendance not by senior physician (adjusted RR 1.97; 95% CI 0.95-4.05) and/or senior physician not called in (adjusted RR 2.53; 95% CI 1.12-5.75), and 5) oxygen saturation not monitored upon admission (adjusted RR 1.45; 95% CI 0.73-2.91). CONCLUSION: Although of limited size, this audit suggests that long preoperative delay in patients with peptic ulcer perforation is associated with factors related to both the internal organisation of the healthcare system, the patient's pathological picture, and the quality of diagnosis and treatment given.
    Udgivelsesdato: 2009-Nov
    Bidragets oversatte titelPreoperative delay in patients with peptic ulcer perforation: a clinical audit from the Danish National Indicator Project
    OriginalsprogDansk
    TidsskriftUgeskrift for læger
    Vol/bind171
    Udgave nummer49
    Sider (fra-til)3605-10
    Antal sider6
    ISSN0041-5782
    StatusUdgivet - 30 nov. 2009

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