Posttranslational Modifications of the Histone 3 Tail and Their Impact on the Activity of Histone Lysine Demethylases In Vitro

Keyphrases

• Post-translational Modification 100%
• Histone Lysine Demethylase 100%
• KDM4A 100%
• Histone H3 100%
• KDM4C 83%
• Demethylation 66%
• Acetylation 50%
• Catalytic Activity 50%
• Demethylase 33%
• H3K9me3 33%
• Phosphorylation 33%
• Peptide Substrate 33%
• Histone Peptides 16%
• Enzyme Kinetics 16%
• Methylation 16%
• Epigenetic Signal 16%
• Histone Tails 16%
• Truncated Version 16%
• Fold Increase 16%
• Kcat 16%
• Catalytic Core 16%
• Kinetic Characteristics 16%
• Methylated Lysine 16%
• Catalytic Efficiency 16%
• Threonine 16%
• Epigenetic Marks 16%

Biochemistry, Genetics and Molecular Biology

• Lysine 100%
• Histone H3 100%
• Histone 100%
• Demethylase 100%
• Posttranslational Modification 100%
• Demethylation 80%
• Acetylation 60%
• Enzymatic Activity 60%
• Catalytic Efficiency 40%
• Epigenetics 40%
• Dynamics 20%
• Phosphorylation 20%
• Enzyme Kinetics 20%
• Methylation 20%
• Threonine 20%

Chemistry

• Lysine 100%
• Histone 100%
• Demethylation 57%
• Catalyst Activity 42%
• Acetylation 42%
• phosphorylation 28%
• Kcat/Km 14%
• Threonine 14%
• Enzyme Kinetic 14%
• methylation 14%