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Post activation depression of the Ia EPSP in motoneurones is reduced in both aged mice and in the G127X SOD1 model of Amyotrophic lateral sclerosis
Anne Hedegaard, Janna Lehnhoff,
Mihai Moldovan
, Lillian Grøndahl,
Claire Francesca Meehan
Motor Control
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Keyphrases
Superoxide Dismutase 1 (SOD1)
100%
Aged Mice
100%
Amyotrophic Lateral Sclerosis
100%
Motoneuron
100%
Post-activation Depression
100%
Spasticity
50%
Anesthesia
33%
Normal Aging
33%
Spike Threshold
16%
Hindfoot
16%
Intracellular Recording
16%
Atropine
16%
Common Peroneal Nerve
16%
Tibial Nerve
16%
Spastic
16%
Reflex
16%
Multiple Comparison Tests
16%
Transgenic Mouse Model
16%
Ia Afferent
16%
Midazolam
16%
Large Mammals
16%
Two-tailed
16%
Time Delay
16%
Causal Role
16%
Multi-electrode
16%
Age-matched
16%
No Significant Difference
16%
Mouse Model
16%
T-test
16%
Ethical Requirements
16%
Wild Mice
16%
C57BL
16%
Heart Rate
16%
Test Size
16%
Monosynaptic Inputs
16%
Neurodegenerative Diseases
16%
Clinical Significance
16%
Neuroscience
Pancuronium Bromide
14%