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PIP2 mediates functional coupling and pharmacology of neuronal KCNQ channels
Robin Y Kim,
Stephan A Pless
, Harley T Kurata
17
Citationer (Scopus)
34
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Keyphrases
Antiepileptic Drugs
12%
Binding Site
12%
C-terminus
12%
Channel Activation
12%
Conformational Change
12%
Deactivation
12%
Deceleration
12%
First-in-class
12%
Function Domain
12%
Functional Coupling
100%
Gating Effect
12%
Hyperpolarizing Shift
12%
Ionic Conductivity
12%
KCNQ Channels
100%
KCNQ2
12%
KCNQ3
12%
Neuronal Excitability
12%
Pharmacology
100%
Phosphatidylinositol 4,5-bisphosphate (PIP2)
100%
Pore-forming
12%
Potassium Channel
12%
Retigabine
100%
Steady State
12%
Voltage Dependence
12%
Voltage Gating
12%
Voltage Sensing
12%
Voltage Sensor
25%
Voltage Sensor Domain
37%
Voltage-clamp Fluorometry
12%
Pharmacology, Toxicology and Pharmaceutical Science
Anticonvulsive Agent
12%
Binding Site
12%
Potassium Channel
12%
Potassium Channel KCNQ
100%
Retigabine
100%