Physiology of astroglia

Alexei Verkhratsky*, Maiken Nedergaard

*Corresponding author af dette arbejde
    360 Citationer (Scopus)

    Abstract

    Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in morphological appearance; they express a multitude of receptors, channels, and membrane transporters. This complement underlies their remarkable adaptive plasticity that defines the functional maintenance of the CNS in development and aging. Astrocytes are tightly integrated into neural networks and act within the context of neural tissue; astrocytes control homeostasis of the CNS at all levels of organization from molecular to the whole organ.

    OriginalsprogEngelsk
    TidsskriftPhysiological Reviews
    Vol/bind98
    Udgave nummer1
    Sider (fra-til)239-389
    Antal sider151
    ISSN0031-9333
    DOI
    StatusUdgivet - 2018

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