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Pharmacology and function of the orphan GPR139 G protein-coupled receptor
Line Vedel, Anne Cathrine Nøhr,
David E Gloriam
,
Hans Bräuner-Osborne
2
Citationer (Scopus)
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Keyphrases
Pharmacology
100%
G Protein-coupled Receptor
100%
GPR139
100%
Physiological Function
42%
Large Families
28%
G Protein
28%
Therapeutic Potential
14%
Plethora
14%
Drug Target
14%
Protein Family
14%
Striatum
14%
Hypothalamic-pituitary Axis
14%
Allosteric Ligands
14%
High-level Expression
14%
Signaling Molecules
14%
Helix
14%
Membrane Protein
14%
Marketed Drugs
14%
Ortho
14%
Orphan Receptor
14%
Arrestin
14%
Aromatic Amino Acids
14%
Ligand Binding Site
14%
Cell Membrane
14%
Binding Site
14%
Human Genome
14%
Transmembrane
14%
Tryptophan
14%
Receptor-interacting Protein Kinase 1 (RIPK1)
14%
Protein Pathway
14%
Druggability
14%
Transmembrane Domain
14%
Functional Potential
14%
Immunology and Microbiology
Agonist
100%
Binding Site
50%
Cell Membrane
25%
Protein Family
25%
Peptides
25%
Corpus Striatum
25%
Retina S Antigen
25%
Amino Acid
25%
Ligand Binding
25%
Human Genome
25%
Thalamus
25%
Allosterism
25%
Hypothalamus
25%
Pharmacophore
25%
Biochemistry, Genetics and Molecular Biology
G Protein Coupled Receptor
100%
Agonist
57%
Binding Site
28%
G Protein
28%
Transmembrane Domain
14%
Pharmacophore
14%
Human Genome
14%
Orphan Receptor
14%
Melanocyte-Stimulating Hormone
14%
Cell Membrane
14%
Protein Family
14%
Arrestin
14%
Adrenocorticotropic Hormone
14%
Allosteric Regulation
14%
Ligand Binding
14%
Amino Acid
14%
Pharmacology, Toxicology and Pharmaceutical Science
G Protein Coupled Receptor
100%
Receptor
57%
Guanine Nucleotide Binding Protein
28%
Endogenous Agonist
28%
Binding Site
28%
Retina S Antigen
14%
Aromatic Amino Acid
14%
Intermedin
14%
Corticotropin
14%