PGC-1alpha and PGC-1beta have both similar and distinct effects on myofiber switching toward an oxidative phenotype.

Medicin og biovidenskab

• Phenotype 100%
• Messenger RNA 94%
• Myosin Heavy Chains 78%
• Protein Isoforms 53%
• Skeletal Muscle Fibers 37%
• Down-Regulation 34%
• Butyryl-CoA Dehydrogenase 30%
• MEF2 Transcription Factors 24%
• Citrate (si)-Synthase 22%
• Glyceraldehyde-3-Phosphate Dehydrogenases 21%
• Myoblasts 19%
• PPAR gamma 18%
• Creatine Kinase 17%
• Glycogen 17%
• L-Lactate Dehydrogenase 16%
• Adenoviridae 16%
• Muscle Cells 15%
• Skeletal Muscle 13%
• Transcription Factors 12%
• Insulin 11%
• Glucose 10%
• Muscles 10%
• Genes 6%