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PGC-1α and fasting-induced PDH regulation in mouse skeletal muscle
Anders Gudiksen
,
Henriette Pilegaard
Cellebiologi og Fysiologi
9
Citationer (Scopus)
62
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Keyphrases
PGC-1
100%
Mouse Skeletal muscle
100%
Pyruvate Dehydrogenase
100%
Skeletal muscle
80%
Fasted State
50%
Sirtuin 3 (SIRT3)
40%
Knock-in Mouse Model
30%
Fed State
20%
Acetylation
20%
Phosphorylation
20%
Protein Content
20%
Pyruvate Dehydrogenase Kinase 4 (PDK4)
20%
Fat Oxidation
20%
High-fat Diet
10%
Floxed
10%
Respiratory Exchange Ratio
10%
Peroxisome Proliferator-activated Receptor-γ coactivator-1α (PGC-1α)
10%
Lysine
10%
PDP1
10%
Substrate Utilization
10%
Pyruvate Dehydrogenase Phosphatase
10%
Protein Level
10%
Littermate Controls
10%
PDK1
10%
Biochemistry, Genetics and Molecular Biology
Skeletal Muscle
100%
Pyruvate Dehydrogenase
100%
Sirtuin
44%
Knockout Mouse
33%
Acetylation
22%
Protein Content
22%
Lysine
11%
Phosphatase
11%
Lung Gas Exchange
11%
Pyruvate Dehydrogenase Kinase
11%
Upregulation
11%
Phosphoinositide-Dependent Kinase-1
11%
PDK4
11%
Peroxisome Proliferator Activated Receptor Gamma Coactivator 1alpha
11%