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Personalized gene silencing therapeutics for Huntington disease
C Kay,
N H Skotte
, A L Southwell, M R Hayden
39
Citationer (Scopus)
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Keyphrases
Huntingtin
100%
Huntington's Disease
100%
Gene Silencing
100%
Single nucleotide Polymorphism
40%
Allele-specific
40%
Target Identification
20%
Novel Solutions
20%
Mutant Huntingtin
20%
Genotype
20%
Novel Therapeutics
20%
CAG Repeat
20%
Safe Treatment
20%
Gene Expression
20%
Non-selective
20%
Genetic Disease
20%
Regulatory Agencies
20%
Population Genetics
20%
Linkage Disequilibrium
20%
Clinical Implementation
20%
Clinical Investigator
20%
Autosomal Dominant Disorder
20%
Genomic Medicine
20%
Gene Transcript
20%
Patient Demographics
20%
CAG Trinucleotide Repeat
20%
Individualized Treatment
20%
Biochemistry, Genetics and Molecular Biology
Huntingtin
100%
Gene Inactivation
100%
Single-Nucleotide Polymorphism
40%
Allele
40%
Trinucleotide Repeat Expansion
20%
CAG Repeat
20%
Gene Linkage Disequilibrium
20%
Gene Expression
20%
Population Genetics
20%
Medical Genetics
20%
Genetic Disorder
20%
Autosomal Dominant Inheritance
20%
Solution and Solubility
20%