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Oxyntomodulin differentially affects glucagon-like peptide-1 receptor beta-arrestin recruitment and signaling through Galpha(s)
Rasmus Jorgensen, Valentina Kubale, Milka Vrecl,
Thue W Schwartz
, Christian E Elling
Institut for Neurovidenskab
93
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Keyphrases
Glucagon-like
100%
β-arrestin Recruitment
100%
A1 Receptor
100%
Oxyntomodulin
100%
Glucagon
37%
GRK2
25%
Full Agonist
25%
Receptor-mediated
12%
Pharmacology
12%
Partial Agonist
12%
Promising Target
12%
Bioluminescence Resonance Energy Transfer Assay
12%
Second Messenger
12%
Type 2 Diabetes Prevention
12%
Obesity
12%
Peptide Hormone
12%
Agricultural and Biological Sciences
Arrestin
100%
Enteroglucagon
100%
Glucagon-Like Peptide 1 Receptor
100%
Agonist
50%
Glucagon
37%
Bioluminescence
12%
Peptide Hormone
12%
Second Messenger
12%
G Protein-Coupled Receptor
12%
Pharmacology, Toxicology and Pharmaceutical Science
Oxyntomodulin
100%
G Protein Coupled Receptor Kinase 2
12%
Biochemistry, Genetics and Molecular Biology
Biased Ligands
12%