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Optimizing sgRNA position markedly improves the efficiency of CRISPR/dCas9-mediated transcriptional repression
Aliaksandra Radzisheuskaya,
Daria Shlyueva
, Iris Müller, Kristian Helin
DanStem
59
Citationer (Scopus)
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Alfabetisk
Biochemistry, Genetics and Molecular Biology
Guide RNA
100%
CRISPR
100%
Transcription Initiation Site
57%
Promoter Region
14%
RNA Sequence
14%
Gene Mapping
14%
Genetic Transcription
14%
Regulatory Element
14%
Gene Function
14%
Gene Repression
14%
Immunology and Microbiology
Clustered Regularly Interspaced Short Palindromic Repeat
100%
Transcription Initiation Site
50%
RNA Sequence
12%
Human Cell
12%
Regulator Gene
12%
Genetic Transcription
12%
Gene Mapping
12%
Gene Function
12%
Gene Repression
12%
Promoter Region
12%
Keyphrases
CRISPR Interference (CRISPRi)
100%
CRISPR-dCas9
100%
Most Reliable Source
14%
Sequence Preference
14%
Guide RNA Design
14%