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One man's side effect is another man's therapeutic opportunity: targeting Kv7 channels in smooth muscle disorders
Thomas Andrew Jepps
, S P Olesen, I A Greenwood
Physiology of circulation, kidney and lung
34
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Keyphrases
Therapeutic Potential
100%
Muscle Disease
100%
Kv7 Channels
100%
Smooth muscle
100%
Retigabine
40%
Muscle System
20%
Bladder
20%
Constipation
20%
Membrane Potential
20%
Clinical Trials
20%
Preterm Labor
20%
First-in-class
20%
Seizure Generation
20%
Neuronal Activity
20%
Hypertension
20%
Anticonvulsant
20%
Novel Mechanism of Action
20%
Pharmacology, Toxicology and Pharmaceutical Science
Retigabine
100%
Muscle Disease
100%
Side Effect
100%
Diseases
50%
Premature Labor
50%
Anticonvulsive Agent
50%
Epilepsy
50%
Clinical Trial
50%
Constipation
50%