TY - JOUR
T1 - Obstructive sleep apnea in obese children and adolescents, treatment methods and outcome of treatment
T2 - A systematic review
AU - Andersen, Ida Gillberg
AU - Holm, Jens-Christian
AU - Homøe, Preben
N1 - Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
PY - 2016/8/1
Y1 - 2016/8/1
N2 - Objectives: To systematically review and discuss the outcome of treating obstructive sleep apnea (OSA) in obese children and adolescents. Methods: In February 2016 Pub Med was searched using a predetermined string to retrieve all relevant articles. The search identified 518 publications. In total 16 articles were included for review using the selected inclusion and exclusion criteria. The PRISMA guidelines was used. Results: OSA was significantly more likely to persist in obese children after adenotonsillectomy. The prevalence of persistent OSA ranged from 33 to 76% in obese children and from 15 to 37% in non-obese children depending on the definition of OSA, the degree of obesity and the age of the study population. The few studies that investigated the effect of weight loss found that OSA improved significantly after intervention and that the prevalence of persistent OSA varied between 10 and 38%. Positive airway pressure was effective for treating OSA, but the mean nightly use was <4 h in two out of three available studies. Conclusion: Obese children benefit less from adenotonsillectomy than normal-weight children. Weight loss improve OSA significantly, but more research is needed to clarify the role of weight loss as treatment for OSA. Positive airway pressure is effective for treating OSA; however, adherence is a challenge.
AB - Objectives: To systematically review and discuss the outcome of treating obstructive sleep apnea (OSA) in obese children and adolescents. Methods: In February 2016 Pub Med was searched using a predetermined string to retrieve all relevant articles. The search identified 518 publications. In total 16 articles were included for review using the selected inclusion and exclusion criteria. The PRISMA guidelines was used. Results: OSA was significantly more likely to persist in obese children after adenotonsillectomy. The prevalence of persistent OSA ranged from 33 to 76% in obese children and from 15 to 37% in non-obese children depending on the definition of OSA, the degree of obesity and the age of the study population. The few studies that investigated the effect of weight loss found that OSA improved significantly after intervention and that the prevalence of persistent OSA varied between 10 and 38%. Positive airway pressure was effective for treating OSA, but the mean nightly use was <4 h in two out of three available studies. Conclusion: Obese children benefit less from adenotonsillectomy than normal-weight children. Weight loss improve OSA significantly, but more research is needed to clarify the role of weight loss as treatment for OSA. Positive airway pressure is effective for treating OSA; however, adherence is a challenge.
KW - Journal Article
KW - Review
U2 - 10.1016/j.ijporl.2016.06.017
DO - 10.1016/j.ijporl.2016.06.017
M3 - Review
C2 - 27368470
SN - 1871-4048
VL - 87
SP - 190
EP - 197
JO - International Journal of Pediatric Otorhinolaryngology Extra
JF - International Journal of Pediatric Otorhinolaryngology Extra
ER -
