Novel monohydroxamate drugs attenuate myocardial reperfusion-induced arrhythmias

Medicin og biovidenskab

• N-methyl acetohydroxamic acid 100%
• Myocardial Reperfusion 61%
• Deferoxamine 51%
• Reperfusion 43%
• Cardiac Arrhythmias 41%
• N-methyl butyrohydroxamic acid 40%
• N-methyl hexanoylhydroxamic acid 39%
• Heart 31%
• Ischemia 24%
• Pharmaceutical Preparations 20%
• Ventricular Fibrillation 17%
• Ventricular Tachycardia 17%
• Isolated Heart Preparation 11%
• Incidence 7%
• Iron 6%
• Antioxidants 6%

Kemiske forbindelser

• Acetohydroxamic Acid 75%
• Desferrioxamine 54%
• Drug 25%
• Reduction 22%
• Acid 12%
• Antioxidant Agent 9%