Abstract
PURPOSE: To investigate whether normal tension glaucoma (NTG) is associated with increased risk of developing dementia/Alzheimer disease (AD).
METHODS: A total of 69 patients with NTG were identified in the case note files in the Glaucoma Clinic, University Hospital of Copenhagen (Rigshospitalet), Denmark from 1980 to 2001. The rate of a subsequent diagnosis of dementia as recorded in nationwide health care registers from 1980 to 2005 was estimated and compared with the rate for the general population [standard mortality rate (SMR) = observed number of cases of dementia/expected number of cases of dementia].
RESULTS: The 69 patients had a median age of 64 years (quartiles 57 and 73) at the time of the diagnosis, and the average follow-up period was 12.7 years. The SMR(dementia) was 0.20 (95% CI 0.01-1.11). No patient developed AD.
CONCLUSION: Normal tension glaucoma was not associated with an increased risk of developing dementia/AD.
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Acta Ophthamologica (Online) |
| Vol/bind | 90 |
| Udgave nummer | 7 |
| Sider (fra-til) | 683-5 |
| Antal sider | 3 |
| ISSN | 1755-3768 |
| DOI | |
| Status | Udgivet - nov. 2012 |
Emneord
- Aged
- Aged, 80 and over
- Alzheimer Disease
- Antihypertensive Agents
- Ciliary Body
- Comorbidity
- Denmark
- Female
- Humans
- Intraocular Pressure
- Laser Coagulation
- Low Tension Glaucoma
- Male
- Middle Aged
- Registries
- Risk Factors
- Trabeculectomy