Nitrogenoxid og sepsis

TY - JOUR

T1 - Nitrogenoxid og sepsis

AU - El-Haj, Lama

AU - Bestle, Morten Heiberg

PY - 2017

Y1 - 2017

N2 - The main purpose of this study is to review the function of nitric oxide during sepsis and septic shock. Futhermore, the study reviews the various physiological functions of nitric oxide in the human body, and how these functions can and have been used clinically. Nitric oxide plays an important role during septic shock in contributing to development of hypotension, multiorgan failure and lack of response to pressor therapy. Elevated concentrations of nitric oxide in both circulation and expiratory air have been found in hu-mans and animals during sepsis and septic shock. Further-more, studies show that nictric oxide plays an important role in the immune system. The physiological effect of nitric oxide has been used in various treatments.

AB - The main purpose of this study is to review the function of nitric oxide during sepsis and septic shock. Futhermore, the study reviews the various physiological functions of nitric oxide in the human body, and how these functions can and have been used clinically. Nitric oxide plays an important role during septic shock in contributing to development of hypotension, multiorgan failure and lack of response to pressor therapy. Elevated concentrations of nitric oxide in both circulation and expiratory air have been found in hu-mans and animals during sepsis and septic shock. Further-more, studies show that nictric oxide plays an important role in the immune system. The physiological effect of nitric oxide has been used in various treatments.

KW - Hemodynamics/physiology

KW - Humans

KW - Lung/physiology

KW - Nitric Oxide/immunology

KW - Sepsis/metabolism

KW - Vasodilator Agents/therapeutic use

M3 - Review

C2 - 29084619

SN - 0041-5782

VL - 179

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

M1 - V01170086

ER -