Nitric oxide-induced changes in endothelial expression of phosphodiesterases 2, 3, and 5

Medicin og biovidenskab

• 2'-phosphodiesterase 100%
• Type 2 Cyclic Nucleotide Phosphodiesterases 77%
• Nitric Oxide 47%
• Endothelial Cells 30%
• 2,2'-(hydroxynitrosohydrazono)bis-ethanamine 29%
• human PDE5A protein 20%
• Cyclic GMP 19%
• Messenger RNA 18%
• Headache 14%
• Phosphodiesterase 3 Inhibitors 12%
• cyclic guanosine monophosphate-adenosine monophosphate 12%
• Up-Regulation 12%
• Phosphodiesterase 5 Inhibitors 10%
• Nitric Oxide Donors 9%
• Cyclic Nucleotides 9%
• Cell Line 9%
• Proteins 9%
• Migraine Disorders 8%
• Cyclic AMP 8%
• Real-Time Polymerase Chain Reaction 6%
• Stroke 5%
• Western Blotting 5%
• Brain 4%