TY - JOUR
T1 - New human milk fat substitutes from butterfat to improve fat absorption
AU - Li, Yanqi
AU - Mu, Huiling
AU - Andersen, Jens Enevold Thaulov
AU - Xu, Xuebing
AU - Meyer, Otto
AU - Ørngreen, Anne
PY - 2010/4
Y1 - 2010/4
N2 - A new human milk fat substitute (HMFS) was produced from butterfat. A 2-week's feeding experiment was performed using three groups of rats with 10 wt.% fat in their feed; the fat was either (1) butterfat-based HMFS + long-chain polyunsaturated fatty acids (LCPUFA), (2) the reference oil + LCPUFA, or (3) the reference oil without LCPUFA. The apparent fat absorption after intake of butterfat-based HMFS (95.9% ± 1.8%) was significantly higher than the other two groups, indicating that much less calcium soap was formed after feeding butterfat-based HMFS. Calcium contents in urines and faeces from the two groups fed LCPUFA in their diet were lower than those without supplementation of LCPUFA, suggesting that LCPUFA could improve calcium absorption by reducing the calcium excretion. It can thus be concluded that the butterfat-based HMFS improves fat absorption, and supplementation of LCPUFA in the formula improves calcium absorption.
AB - A new human milk fat substitute (HMFS) was produced from butterfat. A 2-week's feeding experiment was performed using three groups of rats with 10 wt.% fat in their feed; the fat was either (1) butterfat-based HMFS + long-chain polyunsaturated fatty acids (LCPUFA), (2) the reference oil + LCPUFA, or (3) the reference oil without LCPUFA. The apparent fat absorption after intake of butterfat-based HMFS (95.9% ± 1.8%) was significantly higher than the other two groups, indicating that much less calcium soap was formed after feeding butterfat-based HMFS. Calcium contents in urines and faeces from the two groups fed LCPUFA in their diet were lower than those without supplementation of LCPUFA, suggesting that LCPUFA could improve calcium absorption by reducing the calcium excretion. It can thus be concluded that the butterfat-based HMFS improves fat absorption, and supplementation of LCPUFA in the formula improves calcium absorption.
KW - Former Faculty of Pharmaceutical Sciences
U2 - 10.1016/j.foodres.2009.11.006
DO - 10.1016/j.foodres.2009.11.006
M3 - Journal article
SN - 0963-9969
VL - 43
SP - 739
EP - 744
JO - Food Research International
JF - Food Research International
ER -