Neuropathie optique réversible liée au disulfirame

TY - JOUR

T1 - Neuropathie optique réversible liée au disulfirame

AU - Trélohan, A

AU - Milea, D

N1 - Copyright © 2011 Elsevier Masson SAS. All rights reserved.

PY - 2011/6

Y1 - 2011/6

N2 - Objective: To report a case of bilateral optic neuropathy, possibly caused by disulfiram. Patients and methods: Clinical case report. Results: A 46-year-old patient, treated with disulfiram for the past 4 years for chronic alcoholism, presented with progressive bilateral, painless, severe visual loss, related to optic neuropathy. An extensive work-up did not disclose any other possible cause than a toxic optic neuropathy caused by disulfiram. Discontinuation of disulfiram resulted in rapid, complete visual recovery. Conclusion: Disulfiram can cause toxic optic neuropathy, which can recover after discontinuing the medication, even after a long period of intoxication.

AB - Objective: To report a case of bilateral optic neuropathy, possibly caused by disulfiram. Patients and methods: Clinical case report. Results: A 46-year-old patient, treated with disulfiram for the past 4 years for chronic alcoholism, presented with progressive bilateral, painless, severe visual loss, related to optic neuropathy. An extensive work-up did not disclose any other possible cause than a toxic optic neuropathy caused by disulfiram. Discontinuation of disulfiram resulted in rapid, complete visual recovery. Conclusion: Disulfiram can cause toxic optic neuropathy, which can recover after discontinuing the medication, even after a long period of intoxication.

U2 - 10.1016/j.jfo.2010.11.019

DO - 10.1016/j.jfo.2010.11.019

M3 - Tidsskriftartikel

SN - 0181-5512

VL - 34

SP - 382.e1-3

JO - Journal Francais d'Ophtalmologie

JF - Journal Francais d'Ophtalmologie

IS - 6

ER -