Neural Blockade for Persistent Pain After Breast Cancer Surgery

Nelun Wijayasinghe; Kenneth Geving Andersen; Henrik Kehlet

doi:10.1097/aap.0000000000000101

Neural Blockade for Persistent Pain After Breast Cancer Surgery

Nelun Wijayasinghe, Kenneth Geving Andersen, Henrik Kehlet

Institut for Klinisk Medicin

24 Citationer (Scopus)

Abstract

Persistent pain after breast cancer surgery is predominantly a neuropathic pain syndrome affecting 25% to 60% of patients and related to injury of the intercostobrachial nerve, intercostal nerves, and other nerves in the region. Neural blockade can be useful for the identification of nerves involved in neuropathic pain syndromes or to be used as a treatment in its own right. The purpose of this review was to examine the evidence for neural blockade as a potential diagnostic tool or treatment for persistent pain after breast cancer surgery. In this systematic review, we found only 7 studies (n = 135) assessing blocks directed at 3 neural structures-stellate ganglion, paravertebral plexus, and intercostal nerves-but none focusing on the intercostobrachial nerve. The quality of the studies was low and efficacy inconclusive, suggesting a need for well-designed, high-quality studies for this common clinical problem.

Originalsprog	Engelsk
Tidsskrift	Regional Anesthesia and Pain Medicine
Vol/bind	39
Udgave nummer	4
Sider (fra-til)	272-278
Antal sider	7
ISSN	1098-7339
DOI	https://doi.org/10.1097/aap.0000000000000101
Status	Udgivet - 12 jun. 2014

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10.1097/aap.0000000000000101

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title = "Neural Blockade for Persistent Pain After Breast Cancer Surgery",

abstract = "Persistent pain after breast cancer surgery is predominantly a neuropathic pain syndrome affecting 25% to 60% of patients and related to injury of the intercostobrachial nerve, intercostal nerves, and other nerves in the region. Neural blockade can be useful for the identification of nerves involved in neuropathic pain syndromes or to be used as a treatment in its own right. The purpose of this review was to examine the evidence for neural blockade as a potential diagnostic tool or treatment for persistent pain after breast cancer surgery. In this systematic review, we found only 7 studies (n = 135) assessing blocks directed at 3 neural structures-stellate ganglion, paravertebral plexus, and intercostal nerves-but none focusing on the intercostobrachial nerve. The quality of the studies was low and efficacy inconclusive, suggesting a need for well-designed, high-quality studies for this common clinical problem.",

keywords = "Breast Neoplasms, Female, Humans, Nerve Block, Neuralgia, Pain, Postoperative",

author = "Nelun Wijayasinghe and Andersen, {Kenneth Geving} and Henrik Kehlet",

year = "2014",

month = jun,

day = "12",

doi = "10.1097/aap.0000000000000101",

language = "English",

volume = "39",

pages = "272--278",

journal = "Regional Anesthesia and Pain Medicine",

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publisher = "Lippincott Williams & Wilkins",

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TY - JOUR

T1 - Neural Blockade for Persistent Pain After Breast Cancer Surgery

AU - Wijayasinghe, Nelun

AU - Andersen, Kenneth Geving

AU - Kehlet, Henrik

PY - 2014/6/12

Y1 - 2014/6/12

N2 - Persistent pain after breast cancer surgery is predominantly a neuropathic pain syndrome affecting 25% to 60% of patients and related to injury of the intercostobrachial nerve, intercostal nerves, and other nerves in the region. Neural blockade can be useful for the identification of nerves involved in neuropathic pain syndromes or to be used as a treatment in its own right. The purpose of this review was to examine the evidence for neural blockade as a potential diagnostic tool or treatment for persistent pain after breast cancer surgery. In this systematic review, we found only 7 studies (n = 135) assessing blocks directed at 3 neural structures-stellate ganglion, paravertebral plexus, and intercostal nerves-but none focusing on the intercostobrachial nerve. The quality of the studies was low and efficacy inconclusive, suggesting a need for well-designed, high-quality studies for this common clinical problem.

AB - Persistent pain after breast cancer surgery is predominantly a neuropathic pain syndrome affecting 25% to 60% of patients and related to injury of the intercostobrachial nerve, intercostal nerves, and other nerves in the region. Neural blockade can be useful for the identification of nerves involved in neuropathic pain syndromes or to be used as a treatment in its own right. The purpose of this review was to examine the evidence for neural blockade as a potential diagnostic tool or treatment for persistent pain after breast cancer surgery. In this systematic review, we found only 7 studies (n = 135) assessing blocks directed at 3 neural structures-stellate ganglion, paravertebral plexus, and intercostal nerves-but none focusing on the intercostobrachial nerve. The quality of the studies was low and efficacy inconclusive, suggesting a need for well-designed, high-quality studies for this common clinical problem.

KW - Breast Neoplasms

KW - Female

KW - Humans

KW - Nerve Block

KW - Neuralgia

KW - Pain, Postoperative

U2 - 10.1097/aap.0000000000000101

DO - 10.1097/aap.0000000000000101

M3 - Review

C2 - 24918332

SN - 1098-7339

VL - 39

SP - 272

EP - 278

JO - Regional Anesthesia and Pain Medicine

JF - Regional Anesthesia and Pain Medicine

IS - 4

ER -

Neural Blockade for Persistent Pain After Breast Cancer Surgery

Abstract

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