Natural history of COPD: Focusing on change in FEV1

Jørgen Vestbo; Peter Lange

doi:10.1111/resp.12589

Natural history of COPD: Focusing on change in FEV₁

23 Citationer (Scopus)

Abstract

The natural history of chronic obstructive pulmonary disease (COPD) is usually described with a focus on change in forced expiratory volume in 1 s (FEV₁ ) over time as this allows for exploration of risk factors for an accelerated decline-and thus of developing COPD. From epidemiological studies we have recognized important risk factors such as smoking, exposure to biomass and occupational exposures, but we have also learnt about features such as chronic bronchitis, airway hyper-responsiveness and asthma that seem to accelerate decline in FEV₁ independent of exposures. In addition we are gradually beginning to better link early life events to subsequent risk of disease in adulthood. Although more complicated, our current understanding of COPD has come a long way from being a simple image of smoking leading to poor lungs.

Originalsprog	Engelsk
Tidsskrift	Respirology
Vol/bind	21
Udgave nummer	1
Sider (fra-til)	34-43
Antal sider	10
ISSN	1323-7799
DOI	https://doi.org/10.1111/resp.12589
Status	Udgivet - 1 jan. 2016

Adgang til dokumentet

10.1111/resp.12589

resp.12589Forlagets udgivne version, 380 KB

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/resp.12589

Citationsformater

@article{cd08fd4f5e7b4c8fadd35275445abd99,

title = "Natural history of COPD: Focusing on change in FEV1",

abstract = "The natural history of chronic obstructive pulmonary disease (COPD) is usually described with a focus on change in forced expiratory volume in 1 s (FEV1 ) over time as this allows for exploration of risk factors for an accelerated decline-and thus of developing COPD. From epidemiological studies we have recognized important risk factors such as smoking, exposure to biomass and occupational exposures, but we have also learnt about features such as chronic bronchitis, airway hyper-responsiveness and asthma that seem to accelerate decline in FEV1 independent of exposures. In addition we are gradually beginning to better link early life events to subsequent risk of disease in adulthood. Although more complicated, our current understanding of COPD has come a long way from being a simple image of smoking leading to poor lungs.",

author = "J{\o}rgen Vestbo and Peter Lange",

note = "{\textcopyright} 2015 Asian Pacific Society of Respirology.",

year = "2016",

month = jan,

day = "1",

doi = "10.1111/resp.12589",

language = "English",

volume = "21",

pages = "34--43",

journal = "Respirology",

issn = "1323-7799",

publisher = "Wiley",

number = "1",

}

TY - JOUR

T1 - Natural history of COPD

T2 - Focusing on change in FEV1

AU - Vestbo, Jørgen

AU - Lange, Peter

PY - 2016/1/1

Y1 - 2016/1/1

N2 - The natural history of chronic obstructive pulmonary disease (COPD) is usually described with a focus on change in forced expiratory volume in 1 s (FEV1 ) over time as this allows for exploration of risk factors for an accelerated decline-and thus of developing COPD. From epidemiological studies we have recognized important risk factors such as smoking, exposure to biomass and occupational exposures, but we have also learnt about features such as chronic bronchitis, airway hyper-responsiveness and asthma that seem to accelerate decline in FEV1 independent of exposures. In addition we are gradually beginning to better link early life events to subsequent risk of disease in adulthood. Although more complicated, our current understanding of COPD has come a long way from being a simple image of smoking leading to poor lungs.

AB - The natural history of chronic obstructive pulmonary disease (COPD) is usually described with a focus on change in forced expiratory volume in 1 s (FEV1 ) over time as this allows for exploration of risk factors for an accelerated decline-and thus of developing COPD. From epidemiological studies we have recognized important risk factors such as smoking, exposure to biomass and occupational exposures, but we have also learnt about features such as chronic bronchitis, airway hyper-responsiveness and asthma that seem to accelerate decline in FEV1 independent of exposures. In addition we are gradually beginning to better link early life events to subsequent risk of disease in adulthood. Although more complicated, our current understanding of COPD has come a long way from being a simple image of smoking leading to poor lungs.

U2 - 10.1111/resp.12589

DO - 10.1111/resp.12589

M3 - Journal article

C2 - 26176980

SN - 1323-7799

VL - 21

SP - 34

EP - 43

JO - Respirology

JF - Respirology

IS - 1

ER -

Natural history of COPD: Focusing on change in FEV1

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater

Natural history of COPD: Focusing on change in FEV₁